Evidence map›Paper›PMID 35461692›Full record

SynthesisThe Lancet. Digital health2022

The performance of wearable sensors in the detection of SARS-CoV-2 infection: a systematic review.

Marianna Mitratza, Brianna Mae Goodale, Aizhan Shagadatova, Vladimir Kovacevic, Janneke van de Wijgert, Timo B Brakenhoff, Richard Dobson, Billy Franks, Duco Veen, Amos A Folarin and 4 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in The Lancet. Digital health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 74 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 4 countries.

Marianna MitratzaJulius Global Health, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands. Electronic address: m.mitratza@umcutrecht.nl.
Brianna Mae GoodaleAva AG, Zurich, Switzerland.
Aizhan ShagadatovaJulius Global Health, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Vladimir KovacevicAva AG, Zurich, Switzerland.
Janneke van de WijgertJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Timo B BrakenhoffJulius Clinical Research BV, Zeist, Netherlands.
Richard DobsonInstitute of Health Informatics, University College London, London, UK.
Billy FranksJulius Clinical Research BV, Zeist, Netherlands.
Duco VeenJulius Global Health, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands; Julius Clinical Research BV, Zeist, Netherlands; Optentia Research Program, North-West University, Potchefstroom, South Africa.
Amos A FolarinInstitute of Health Informatics, University College London, London, UK; National Institute for Health Research Maudsley Biomedical Research Centre, King's College London, London, UK; Department of Biostatistics and Health Informatics, South London and Maudsley NHS Foundation Trust, London, UK.
Pieter StolkJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Diederick E GrobbeeJulius Global Health, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands; Julius Clinical Research BV, Zeist, Netherlands.
Maureen CroninAva AG, Zurich, Switzerland.
George S DownwardJulius Global Health, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Oklahoma State University Center for Health Sciences · USUtrecht University · NLKing's College London · GBNorth-West University · ZANational Institute for Health Research · GBUniversity College London · GB

Funding

Medical Research Council MC_PC_17214
6 · The paper itself

Abstract

Containing the COVID-19 pandemic requires rapidly identifying infected individuals. Subtle changes in physiological parameters (such as heart rate, respiratory rate, and skin temperature), discernible by wearable devices, could act as early digital biomarkers of infections. Our primary objective was to assess the performance of statistical and algorithmic models using data from wearable devices to detect deviations compatible with a SARS-CoV-2 infection. We searched MEDLINE, Embase, Web of Science, the Cochrane Central Register of Controlled Trials (known as CENTRAL), International Clinical Trials Registry Platform, and ClinicalTrials.gov on July 27, 2021 for publications, preprints, and study protocols describing the use of wearable devices to identify a SARS-CoV-2 infection. Of 3196 records identified and screened, 12 articles and 12 study protocols were analysed. Most included articles had a moderate risk of bias, as per the National Institute of Health Quality Assessment Tool for Observational and Cross-Sectional Studies. The accuracy of algorithmic models to detect SARS-CoV-2 infection varied greatly (area under the curve 0·52-0·92). An algorithm's ability to detect presymptomatic infection varied greatly (from 20% to 88% of cases), from 14 days to 1 day before symptom onset. Increased heart rate was most frequently associated with SARS-CoV-2 infection, along with increased skin temperature and respiratory rate. All 12 protocols described prospective studies that had yet to be completed or to publish their results, including two randomised controlled trials. The evidence surrounding wearable devices in the early detection of SARS-CoV-2 infection is still in an early stage, with a limited overall number of studies identified. However, these studies show promise for the early detection of SARS-CoV-2 infection. Large prospective, and preferably controlled, studies recruiting and retaining larger and more diverse populations are needed to provide further evidence.

Indexed as

COVID-19Wearable Electronic DevicesCross-Sectional StudiesHumansPandemicsProspective StudiesSARS-CoV-2

Identifiers

PMID35461692
PMCPMC9020803
OpenAlexW4224304220

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.