Evidence map›Paper›PMID 35461436›Full record

ArticleArchives of microbiology2022

Molecular detection of Papillomavirus and immunohistochemical investigation of p53 gene expressions in bovine papillomas and fibropapillomas.

Karakurt Emin, Coskun Nuvit, Dag Serpil, Beytut Enver, Veysel Soydal Ataseven, Yilmaz Volkan, Dogan Fırat, Nuhoglu Hilmi, Ermutlu Celal Sahin, Aydin Ugur and 2 more

Erratum issuedAbstract read
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In one paragraph

Article in Archives of microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Karakurt EminDepartment of Pathology, Faculty of Veterinary Medicine, Kafkas University, Kars, Turkey. mehmeteminkarakurt@hotmail.com.ORCID http://orcid.org/0000-0003-2019-3690
Coskun NuvitDepartment of Virology, Faculty of Veterinary Medicine, Kafkas University, Kars, Turkey.ORCID http://orcid.org/0000-0001-7642-6460
Dag SerpilDepartment of Pathology, Faculty of Veterinary Medicine, Kafkas University, Kars, Turkey.ORCID http://orcid.org/0000-0001-7667-689X
Beytut EnverDepartment of Pathology, Faculty of Veterinary Medicine, Kafkas University, Kars, Turkey.ORCID http://orcid.org/0000-0003-3360-2940
Veysel Soydal AtasevenDepartment of Virology, Faculty of Veterinary Medicine, Mustafa Kemal University, Hatay, Turkey.ORCID http://orcid.org/0000-0003-0802-0826
Yilmaz VolkanDepartment of Virology, Faculty of Veterinary Medicine, Kafkas University, Kars, Turkey.ORCID http://orcid.org/0000-0003-2752-5360
Dogan FıratDepartment of Virology, Faculty of Veterinary Medicine, Mustafa Kemal University, Hatay, Turkey.ORCID http://orcid.org/0000-0001-8656-3645
Nuhoglu HilmiDepartment of Pathology, Faculty of Veterinary Medicine, Kafkas University, Kars, Turkey.ORCID http://orcid.org/0000-0003-2530-2542
Ermutlu Celal SahinDepartment of Surgery, Faculty of Veterinary Medicine, Kafkas University, Kars, Turkey.ORCID http://orcid.org/0000-0002-8923-7682
Aydin UgurDepartment of Surgery, Faculty of Veterinary Medicine, Kafkas University, Kars, Turkey.ORCID http://orcid.org/0000-0001-5756-4841
Kuru MushapDepartment of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Kafkas University, Kars, Turkey.ORCID http://orcid.org/0000-0003-4409-251X
Yildiz AyferDepartment of Pathology, Faculty of Veterinary Medicine, Kafkas University, Kars, Turkey.ORCID http://orcid.org/0000-0002-6569-5435
Kafkas University · TRMustafa Kemal University · TR

Funding

Kafkas Üniversitesi 2019-TS-31
6 · The paper itself

Abstract

Papilloma and fibropapilloma cases are quite common in cattle breeding, which cause economic losses due to decrease in the production of milk, meat, and also impair the quality of hide. In this study, we aimed to determine viral etiology and investigate p53 expression levels with immunohistochemical methods from a total of 30 cases. The study material was collected between 2013 and 2021 in Kars, Turkey. Paraffin embedded tissues were used for earlier cases in which the freshly specimens could not be provided. Cases were investigated for papillomavirus etiology with polymerase chain reaction (PCR) using FAP59/FAP64 and MY09/MY11 primer pairs. In 20 of the 30 cases papillomaviruses were identified, and 10 cases were identified as Bovine papillomavirus-1 (BPV-1), 1 case as BPV-2, 1 case as BPV-12, and 1 case as equus caballus papillomavirus 2 (EcPV-2) after sequence analysis. p53 immunostaining was also performed, and the cases were graded according to the positively stained cells. In conclusion BPV-12 was detected for the first time in our country, EcPV-2 was detected first time in cattle indicating cross species infection and p53 was staining most evident in BPV-1 and BPV-2 cases and BPV-12 and EcPV-2 was not stained.

Indexed as

Bovine papillomavirus 1Cattle DiseasesPapillomaAnimalsCattleDNA, ViralGene ExpressionPapillomaviridaeTumor Suppressor Protein p53DNA, ViralTumor Suppressor Protein p53CattleImmunohistochemistryp53PapillomaPolymerase chain reaction

Identifiers

PMID35461436
OpenAlexW4224318639

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.