Evidence map›Paper›PMID 35461220›Full record

ArticleBMC infectious diseases2022

Improving access to pre-exposure prophylaxis for adolescent girls and young women: recommendations from healthcare providers in eastern Zimbabwe.

Morten Skovdal, Phyllis Magoge-Mandizvidza, Freedom Dzamatira, Rufurwokuda Maswera, Constance Nyamukapa, Ranjeeta Thomas, Owen Mugurungi, Simon Gregson

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Morten SkovdalDepartment of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen, Denmark. m.skovdal@sund.ku.dk.
Phyllis Magoge-MandizvidzaManicaland Centre for Public Health Research, Biomedical Research and Training Institute, Harare, Zimbabwe.
Freedom DzamatiraManicaland Centre for Public Health Research, Biomedical Research and Training Institute, Harare, Zimbabwe.
Rufurwokuda MasweraManicaland Centre for Public Health Research, Biomedical Research and Training Institute, Harare, Zimbabwe.
Constance NyamukapaManicaland Centre for Public Health Research, Biomedical Research and Training Institute, Harare, Zimbabwe.
Ranjeeta ThomasDepartment of Health Policy, London School of Economics and Political Science, London, UK.
Owen MugurungiAIDS and TB Programme, Ministry of Health and Child Welfare, Harare, Zimbabwe.
Simon GregsonManicaland Centre for Public Health Research, Biomedical Research and Training Institute, Harare, Zimbabwe.
Biomedical Research and Training Institute · ZWLondon School of Economics and Political Science · GBMinistry of Health and Child Welfare · ZWUniversity of Copenhagen · DK

Funding

Multi-Level Behavioral Economics and Community Psychology Approaches to Strengthen HIV Prevention Cascades in Adolescent Girls and Young Women in East ZimbabweR01MH114562 · NIMH · IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE · PI GREGSON, SIMON ANTHONY JOHN, HALLETT, TIMOTHY · 2017 to 2020
$2.6M
Medical Research Council MR/R015600/1NIMH NIH HHS R01 MH114562NIMH NIH HHS R01MH114562-01
6 · The paper itself

Abstract

backgroundIn sub-Saharan Africa, adolescent girls and young women (AGYW) are at high risk of acquiring HIV. A growing number of sub-Saharan African countries are beginning to avail pre-exposure prophylaxis, or PrEP, but with limited success. Unpacking strategies to overcome barriers to the uptake of PrEP is critical to prevent HIV amongst AGYW. This article explores health professionals' views and recommendations on what is required to increase uptake of PrEP.

methodsThe study draws on interview data from 12 providers of HIV prevention services in eastern Zimbabwe. The healthcare providers were purposefully recruited from a mix of rural and urban health facilities offering PrEP. The interviews were transcribed and imported into NVivo 12 for thematic coding and network analysis.

resultsOur analysis revealed six broad strategies and 15 concrete recommendations which detail the range of elements healthcare providers consider central for facilitating engagement with PrEP. The healthcare providers called for: (1) PrEP marketing campaigns; (2) youth-friendly services or corners; (3) improved PrEP delivery mechanisms; (4) improvements in PrEP treatment; (5) greater engagement with key stakeholders, including with young people themselves; and (6) elimination of costs associated with PrEP use. These recommendations exemplify an awareness amongst healthcare providers that PrEP access is contingent on a range of factors both inside and outside of the clinical setting.

conclusionsHealthcare providers are at the frontline of the HIV epidemic response. Their community-embeddedness, coupled with their interactions and encounters with AGYW, make them well positioned to articulate context-specific measures for improving access to PrEP. Importantly, the breadth of their recommendations suggests recognition of PrEP use as a complex social practice that requires integration of a combination of interventions, spanning biomedical, structural, and behavioural domains.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisAdolescentFemaleHealth PersonnelHumansZimbabweAnti-HIV AgentsHealth servicesHIVPrEPPreventionZimbabwe

Identifiers

PMID35461220
PMCPMC9035262
OpenAlexW4224244582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.