Evidence map›Paper›PMID 35460774›Full record

ArticleThe Science of the total environment2022

In-utero exposure to indoor air pollution or tobacco smoke and cognitive development in a South African birth cohort study.

Grace M Christensen, Claire Rowcliffe, Junyu Chen, Aneesa Vanker, Nastassja Koen, Meaghan J Jones, Nicole Gladish, Nadia Hoffman, Kirsten A Donald, Catherine J Wedderburn and 4 more

Abstract read
In one paragraph

Article in The Science of the total environment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Grace M ChristensenDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Claire RowcliffeDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Junyu ChenDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Aneesa VankerDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, University of Cape Town, South Africa.
Nastassja KoenNeuroscience Institute, University of Cape Town, Cape Town, South Africa; Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa; South African Medical Research Council (SAMRC) Unit on Risk and Resilience in Mental Disorders, University of Cape Town, Cape Town, South Africa.
Meaghan J JonesDepartment of Biochemistry and Medical Genetics, University of Manitoba, Children's Hospital Research, Institute of Manitoba, Winnipeg, Canada.
Nicole GladishDepartment of Medical Genetics, University of British Columbia, Vancouver, BC, Canada; BC Children's Hospital Research Institute, Vancouver, BC, Canada; Centre for Molecular Medicine and Therapeutics, Vancouver, BC, Canada.
Nadia HoffmanNeuroscience Institute, University of Cape Town, Cape Town, South Africa; Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.
Kirsten A DonaldDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, University of Cape Town, South Africa; Neuroscience Institute, University of Cape Town, Cape Town, South Africa.
Catherine J WedderburnDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, University of Cape Town, South Africa; Neuroscience Institute, University of Cape Town, Cape Town, South Africa; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK.
Michael S KoborDepartment of Medical Genetics, University of British Columbia, Vancouver, BC, Canada; BC Children's Hospital Research Institute, Vancouver, BC, Canada; Centre for Molecular Medicine and Therapeutics, Vancouver, BC, Canada.
Heather J ZarDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, University of Cape Town, South Africa; South African Medical Research Council (SAMRC) Unit on Risk and Resilience in Mental Disorders, University of Cape Town, Cape Town, South Africa.
Dan J SteinNeuroscience Institute, University of Cape Town, Cape Town, South Africa; Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa; South African Medical Research Council (SAMRC) Unit on Risk and Resilience in Mental Disorders, University of Cape Town, Cape Town, South Africa.
Anke HülsDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA; Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, USA. Electronic address: anke.huels@emory.edu.

Funding

Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI William Michael Caudle · 2013 to 2026
$22.6M
Graduate and Postdoctoral Training in ToxicologyT32ES012870 · NIEHS · EMORY UNIVERSITY · PI Carmen Joseph Marsit · 2004 to 2026
$9.1M
Maternal Traumatic Stress and Child Development: Epigenetic LinksR21HD085849 · NICHD · HARVARD SCHOOL OF PUBLIC HEALTH · PI KOENEN, KARESTAN C, STEIN, DAN JOSEPH · 2015 to 2016
$323k
NICHD NIH HHS R21 HD085849NIEHS NIH HHS P30 ES019776NIEHS NIH HHS T32 ES012870Wellcome Trust
6 · The paper itself

Abstract

BACKGROUND AND

aimsThere is increasing evidence indicating that air pollution exposure is associated with neuronal damage. Since pregnancy is a critical window of vulnerability, air pollution exposure during this period could have adverse effects on neurodevelopment. This study aims 1) to analyze associations of prenatal exposure to indoor air pollution (particulate matter with diameters ≤10 μm, PM

methodsData of 734 children from the South African Drakenstein Child Health Study were analyzed. Prenatal PM

resultsAn increase of one interquartile range in natural-log transformed PM

conclusionWe found an association of prenatal exposure to indoor air pollution (PM

Indexed as

Air PollutantsAir PollutionAir Pollution, IndoorPrenatal Exposure Delayed EffectsTobacco Smoke PollutionBirth CohortCognitionCohort StudiesFemaleHumansInfantMaternal ExposureNicotianaParticulate MatterPregnancySouth AfricaAir PollutantsParticulate MatterTobacco Smoke PollutionAir pollutionEnvironmental epidemiologyEpigenomicsNeurodevelopmentParticulate matter

Identifiers

PMID35460774
PMCPMC9177804

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.