Evidence map›Paper›PMID 35460596›Full record

ReviewChemistry, an Asian journal2022

Recent Advances in 1,2-Amino(hetero)arylation of Alkenes.

Yungeun Kwon, Qiu Wang

Abstract readReview
In one paragraph

Review in Chemistry, an Asian journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Arylthianthrenium Salts for Triplet Energy Transfer Catalysis.Journal of the American Chemical Society · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yungeun KwonDepartment of Chemistry, Duke University, Durham, North Carolina, 27708, USA.
Qiu WangDepartment of Chemistry, Duke University, Durham, North Carolina, 27708, USA.ORCID http://orcid.org/0000-0002-6803-9556

Funding

New Methods for the Synthesis and Study of Bioactive Nitrogen-Containing MoleculesR01GM118786 · NIGMS · DUKE UNIVERSITY · PI WANG, QIU · 2017 to 2024
$2.6M
Duke University and the National Institutes of Health GM118786NIGMS NIH HHS R01 GM118786
6 · The paper itself

Abstract

Alkene amino(hetero)arylation presents a highly efficient and straightforward strategy for direct installation of amino groups and heteroaryl rings across a double bond simultaneously. An extensive array of practical transformations has been developed via alkene difunctionalization approach to access a broad range of medicinally valuable (hetero)arylethylamine motifs. This review presents recent progress in 1,2-amino(hetero)arylation of alkenes organized in three different modes. First, intramolecular transformations employing C, N-tethered alkenes will be introduced. Next, two-component reactions will be discussed with different combination of precursors, N-tethered alkenes and external aryl precursor, C-tethered alkenes and external amine precursor, or C, N-tethered reagents, and alkenes. Last, three-component intermolecular amino(hetero)arylation reactions will be covered.

Indexed as

AlkenesAminesAminationCatalysisAlkenesAminesalkenesaminationcatalysisdifunctionalization(hetero)arylation(hetero)arylethylamine

Identifiers

PMID35460596
PMCPMC9357224

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.