ArticleJournal of biophotonics2022
Longitudinal assessment of the effect of alkali burns on corneal biomechanical properties using optical coherence elastography.
Article in Journal of biophotonics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Nanosensitive optical coherence tomography to monitor corneal burn and treatment response in vivo.Biomedical optics express · 2026Article
- Ultrafast line-field holographic elastography with single excitation for corneal biomechanical characterization.Biomedical optics express · 2025Article
- Determinants of Human Corneal Mechanical Wave Dispersion for In Vivo Optical Coherence Elastography.Translational vision science & technology · 2025Article
- Imatinib@glycymicelles entrapped in hydrogel: preparation, characterization, and therapeutic effect on corneal alkali burn in mice.Drug delivery and translational research · 2025Article
- De-Differentiation of Corneal Epithelial Cells Into Functional Limbal Epithelial Stem Cells After the Ablation of Innate Stem Cells.Investigative ophthalmology & visual science · 2024Article
- In Vivo Optical Coherence Elastography Unveils Spatial Variation of Human Corneal Stiffness.IEEE transactions on bio-medical engineering · 2024Article
- Acute alcohol consumption modulates corneal biomechanical properties as revealed by optical coherence elastography.Journal of biomechanics · 2024Article
- Squishy matters - Corneal mechanobiology in health and disease.Progress in retinal and eye research · 2024Review
- Simultaneous tensile and shear measurement of the human cornea in vivo using S0- and A0-wave optical coherence elastography.Acta biomaterialia · 2024Article
- Optical coherence elastography measures the biomechanical properties of theJournal of biomedical optics · 2024Article
- Multifocal acoustic radiation force-based reverberant optical coherence elastography for evaluation of ocular globe biomechanical properties.Journal of biomedical optics · 2023Article
- Article
- Identification of the Vibrational Optical Coherence Tomography Corneal Cellular Peak.Translational vision science & technology · 2023Article
- Hyaluronan Modulates the Biomechanical Properties of the Cornea.Investigative ophthalmology & visual science · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Eye injury due to alkali burn is a severe ocular trauma that can profoundly affect corneal structure and function, including its biomechanical properties. Here, we assess the changes in the mechanical behavior of mouse corneas in response to alkali-induced injury by conducting longitudinal measurements using optical coherence elastography (OCE). A non-contact air-coupled ultrasound transducer was used to induce elastic waves in control and alkali-injured mouse corneas in vivo, which were imaged with phase-sensitive optical coherence tomography. Corneal mechanical properties were estimated using a modified Rayleigh-Lamb wave model, and results show that Young's modulus of alkali-burned corneas were significantly greater than that of their healthy counterparts on days 7 (p = 0.029) and 14 (p = 0.026) after injury. These findings, together with the changes in the shear viscosity coefficient postburn, indicate that the mechanical properties of the alkali-burned cornea are significantly modulated during the wound healing process.
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