Evidence map›Paper›PMID 35460515›Full record

ArticleEuropean geriatric medicine2022

Accuracy, feasibility and predictive ability of different frailty instruments in an acute geriatric setting.

Rafael Bielza, Cristina Balaguer, Francisco Zambrana, Estefanía Arias, Israel J Thuissard, Ana Lung, Carlos Oñoro, Patricia Pérez, Cristina Andreu-Vázquez, Marta Neira and 3 more

Open access · hybridAbstract read
In one paragraph

Article in European geriatric medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Hospital-associated decline: A concept analysis.International journal of nursing studies advances · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Rafael BielzaDepartment of Geriatric Medicine, Hospital Universitario Infanta Sofía, Paseo de Europa 37, 28007, San Sebastián de los Reyes, Spain. rafael.bielza@salud.madrid.org.ORCID 0000-0001-5655-6516
Cristina BalaguerDepartment of Medicine, Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Madrid, Spain.
Francisco ZambranaDepartment of Medicine, Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Madrid, Spain.
Estefanía AriasDepartment of Geriatric Medicine, Hospital Universitario Infanta Sofía, Paseo de Europa 37, 28007, San Sebastián de los Reyes, Spain.
Israel J ThuissardDepartment of Medicine, Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Madrid, Spain.
Ana LungDepartment of Geriatric Medicine, Hospital Universitario Infanta Sofía, Paseo de Europa 37, 28007, San Sebastián de los Reyes, Spain.
Carlos OñoroDepartment of Geriatric Medicine, Hospital Universitario Infanta Sofía, Paseo de Europa 37, 28007, San Sebastián de los Reyes, Spain.
Patricia PérezDepartment of Geriatric Medicine, Hospital Universitario Infanta Sofía, Paseo de Europa 37, 28007, San Sebastián de los Reyes, Spain.
Cristina Andreu-VázquezDepartment of Medicine, Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Madrid, Spain.
Marta NeiraDepartment of Geriatric Medicine, Hospital Universitario Infanta Sofía, Paseo de Europa 37, 28007, San Sebastián de los Reyes, Spain.
Noemi AnguitaDepartment of Geriatric Medicine, Hospital Universitario Infanta Sofía, Paseo de Europa 37, 28007, San Sebastián de los Reyes, Spain.
Carmen SáezDepartment of Geriatric Medicine, Hospital Universitario Infanta Sofía, Paseo de Europa 37, 28007, San Sebastián de los Reyes, Spain.
Eva María Fernández de la PuenteDepartment of Geriatric Medicine, Hospital Central de la Cruz Roja San José y Santa Adela, Madrid, Spain.
Hospital Universitario Infanta Sofía · ESUniversidad Europea de Madrid · ESHospital Central de la Cruz Roja San José y Santa Adela · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo analyze the feasibility, accuracy and the ability of different frailty instruments to predict adverse outcomes.

methodsA prospective cohort study was conducted in patients ≥ 70 years admitted to the acute care setting (ACS). Feasibility and prevalence of frailty were assessed by FRAIL, Clinical Frailty Scale (CFS), hand grip strength (HGS) and the Spanish Frailty-VIG. Receiver operator characteristic (ROC) curves and area under the curve (AUC) were performed to identify frailty according to each instrument, setting VIG as the reference. For each instrument, multiple logistic regressions were used to examine the effect of frailty on primary outcome (i.e., three-month mortality) and secondary outcomes (i.e., in-hospital mortality, length of stay, institutionalization, functional decline and 30-day readmission).

resultsA total of 185 patients were included, with a median age of 89 years. The feasibility of the instruments was 100%, except for HGS (67%). The prevalence of frailty varied from 65.2% (FRAIL) to 86.7% (VIG). AUCs against VIG ranged from 0.69 (95% confidence interval [CI] 0.57-0.81: FRAIL) to 0.77 (95% CI 63.5-90.2: CFS). Frail patients defined by FRAIL were 2.7times more likely to have a prolonged length of stay than non-frail patients (95% CI 1.385-5.416). Three-month mortality occurred more among frail patients, either defined by FRAIL (OR 2.5; 95% CI 1.072-5.881) or CFS (OR 3.7; 95% CI 1.255-10.812), than in non-frail patients.

conclusionThe four instruments had high feasibility providing variable prevalence of frailty. FRAIL and CFS predicted well for three-month mortality, and FRAIL also for length of stay. However, none of the instruments predicted for the other secondary outcomes of the study.

Indexed as

FrailtyAgedAged, 80 and overFeasibility StudiesFrail ElderlyGeriatric AssessmentHand StrengthHumansProspective StudiesAccuracyAcute care settingFeasibilityFrailty

Identifiers

PMID35460515
PMCPMC9034644
OpenAlexW4224236953

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.