Evidence map›Paper›PMID 35460506›Full record

ArticleJournal of ultrasound2022

Assessment of Contrast-Enhanced Ultrasound (CEUS) and Computed Tomography (CT) diagnostic accuracy in the evaluation of challenging cystic renal masses.

Lorenzo Angelini, Eugenio Gioulis, Nicoletta Civitareale, Antonio Granata, Christian Zanza, Yaroslava Longhitano, Angelica Zago, Piernicola Machin, Fabio Canal, Armando Serao and 2 more

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In one paragraph

Article in Journal of ultrasound, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Lorenzo AngeliniDepartment of Surgery, Section of Urology, SS Antonio and Biagio and Cesare Arrigo Hospital, Via Venezia, 16, 15121, Alessandria, Italy. lorenzo_t_angelini@yahoo.it.ORCID http://orcid.org/0000-0003-2655-9892
Eugenio GioulisDepartment of Radiology, Conegliano Hospital, Conegliano, Italy.
Nicoletta CivitarealeDepartment of Radiology, Conegliano Hospital, Conegliano, Italy.
Antonio GranataNephrology and Dialysis Unit, Emergency Hospital "Cannizzaro", Catania, Italy.
Christian ZanzaDepartment of Emergency Medicine, Anesthesia and Critical Care, Michele and Pietro Ferrero Hospital, Verduno, Italy.
Yaroslava LonghitanoDepartment of Anesthesia and Critical Care, SS Antonio and Biagio and Cesare Arrigo Hospital, Alessandria, Italy.
Angelica ZagoDepartment of Radiology, Conegliano Hospital, Conegliano, Italy.
Piernicola MachinDepartment of Pathology, Conegliano Hospital, Conegliano, Italy.
Fabio CanalDepartment of Pathology, Conegliano Hospital, Conegliano, Italy.
Armando SeraoDepartment of Surgery, Section of Urology, SS Antonio and Biagio and Cesare Arrigo Hospital, Via Venezia, 16, 15121, Alessandria, Italy.
Gianluca PiccoliDepartment of Radiology, Conegliano Hospital, Conegliano, Italy.
Salvatore ValerioDepartment of Surgery, Section of Urology, Conegliano Hospital, Conegliano, Italy.
Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo · ITOspedale Cannizzaro · ITOspedale San Pietro Fatebenefratelli · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the diagnostic accuracy of contrast-enhanced ultrasound (CEUS) and computed tomography (CT) within Bosniak IIF/III categories.

methodsAfter cystic renal mass diagnosis by contrast-enhanced CT, all patients with Bosniak score ≥ II also underwent CEUS between March 2017 and March 2019. Their exams were retrospectively analyzed. One experienced uro-radiologist performed every CEUS and reviewed the exams according to the EFSUMB 2020 Position Statement, while blinded to clinical data. CT Bosniak scores were retrospectively given blindly by two uro-radiologists (CT 1 and CT 2). We compared CEUS, CT 1 and CT 2 scores to clinical findings and histological tests. Clinical performance characteristics and area under the receiver operating characteristic (ROC) curves (AUCs) were determined separately for CEUS and CT, and then compared.

results101 cystic masses were analyzed. In Bosniak categories IIF and III, the AUCs were 0.854 for CT 1, 0.779 for CT 2, and 0.746 for CEUS.

conclusionDespite some statistical limitations, this study confirms that among cystic renal masses, those classified as Bosniak IIF and III are the most difficult to assess. The diagnostic performances of CEUS and CT are similar within this group. However, in experienced hands, CEUS could be valuable in further evaluation of ambiguous cystic masses, and in more ductile, safer, and cost-effective surveillance of those classified as Bosniak IIF and III. When challenging cystic renal masses occur, CEUS is a useful tool for clinical management and for the follow-up of non-surgical lesions.

Indexed as

Kidney Diseases, CysticTomography, X-Ray ComputedContrast MediaHumansKidneyRetrospective StudiesUltrasonographyContrast MediaCEUSComparisonCTCystic renal massesDiagnostic accuracyKidneyRenal cysts

Identifiers

PMID35460506
PMCPMC9705654
OpenAlexW4224314303

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.