ArticleGenetics2022
The early history of the eye-antennal disc of Drosophila melanogaster.
Article in Genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 16 citations in OpenAlex.
- Hippo signaling regulates dorsoventral patterning iniScience · 2026Article
- Polycomb Group Proteins inBiology · 2026Review
- N-acetylcysteine suppresses retinal defects in Drosophila models of SNRNP200-associated retinitis pigmentosa.Human molecular genetics · 2026Article
- An RNAi-based platform for spatiotemporal control of histone gene expression during animal development.Epigenetics & chromatin · 2026Article
- Differential regulation of eye specification in Drosophila by Polycomb Group epigenetic repressors.Development (Cambridge, England) · 2025Article
- Deep conservation complemented by novelty and innovation in the insect eye ground plan.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- TheFrontiers in neuroscience · 2025Article
- An inherited TBX3 alteration in a prenatal case of ulnar-mammary syndrome: Clinical assessment and functional characterization in Drosophila melanogaster.Journal of cellular physiology · 2024Article
- A Rapid, Simple Workflow for Quantification of External Adult Drosophila Structures.Journal of visualized experiments : JoVE · 2024Article
- Control of fate specification within the dorsal head of Drosophila melanogaster.Development (Cambridge, England) · 2024Article
- Polycomb safeguards imaginal disc specification through control of the Vestigial-Scalloped complex.Development (Cambridge, England) · 2023Article
- Polycomb safeguards imaginal disc specification through control of the Vestigial-Scalloped complex.bioRxiv : the preprint server for biology · 2023Article
- Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye.Developmental cell · 2023Article
- Article
- Creating the eye-antennal disc by fission.Genetics · 2023Article
- Patterning of theFrontiers in cell and developmental biology · 2023Review
- Tissue dissociation for single-cell and single-nuclei RNA sequencing for low amounts of input material.Frontiers in zoology · 2022Article
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2 authors at 1 institution in 1 country.
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Abstract
A pair of eye-antennal imaginal discs give rise to nearly all external structures of the adult Drosophila head including the compound eyes, ocelli, antennae, maxillary palps, head epidermis, and bristles. In the earliest days of Drosophila research, investigators would examine thousands of adult flies in search of viable mutants whose appearance deviated from the norm. The compound eyes are dispensable for viability and perturbations to their structure are easy to detect. As such, the adult compound eye and the developing eye-antennal disc emerged as focal points for studies of genetics and developmental biology. Since few tools were available at the time, early researchers put an enormous amount of thought into models that would explain their experimental observations-many of these hypotheses remain to be tested. However, these "ancient" studies have been lost to time and are no longer read or incorporated into today's literature despite the abundance of field-defining discoveries that are contained therein. In this FlyBook chapter, I will bring these forgotten classics together and draw connections between them and modern studies of tissue specification and patterning. In doing so, I hope to bring a larger appreciation of the contributions that the eye-antennal disc has made to our understanding of development as well as draw the readers' attention to the earliest studies of this important imaginal disc. Armed with the today's toolkit of sophisticated genetic and molecular methods and using the old papers as a guide, we can use the eye-antennal disc to unravel the mysteries of development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.