Evidence map›Paper›PMID 35460369›Full record

ReviewParasitology research2022

Malaria diagnostic methods with the elimination goal in view.

Olukunle O Oyegoke, Leah Maharaj, Oluwasegun P Akoniyon, Illiya Kwoji, Alexandra T Roux, Taiye S Adewumi, Rajendra Maharaj, Bolanle T Oyebola, Matthew A Adeleke, Moses Okpeku

Abstract readReview
In one paragraph

Review in Parasitology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  17. Molecular Characterization ofTropical medicine and infectious disease · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Olukunle O OyegokeDiscipline of Genetics School of Life Sciences, University of KwaZulu-Natal, Westville, Durban, South Africa.
Leah MaharajDiscipline of Genetics School of Life Sciences, University of KwaZulu-Natal, Westville, Durban, South Africa.
Oluwasegun P AkoniyonDiscipline of Genetics School of Life Sciences, University of KwaZulu-Natal, Westville, Durban, South Africa.
Illiya KwojiDiscipline of Genetics School of Life Sciences, University of KwaZulu-Natal, Westville, Durban, South Africa.
Alexandra T RouxDiscipline of Genetics School of Life Sciences, University of KwaZulu-Natal, Westville, Durban, South Africa.
Taiye S AdewumiDiscipline of Genetics School of Life Sciences, University of KwaZulu-Natal, Westville, Durban, South Africa.
Rajendra MaharajOffice of Malaria Research, Medical Research Council, Durban, South Africa.
Bolanle T OyebolaWentworth Hospital, Durban, South Africa.
Matthew A AdelekeDiscipline of Genetics School of Life Sciences, University of KwaZulu-Natal, Westville, Durban, South Africa.
Moses OkpekuDiscipline of Genetics School of Life Sciences, University of KwaZulu-Natal, Westville, Durban, South Africa. okpekum@ukzn.ac.za.ORCID http://orcid.org/0000-0002-8337-6294

Funding

National Research Foundation 120368
6 · The paper itself

Abstract

Malaria control measures have been in use for years but have not completely curbed the spread of infection. Ultimately, global elimination is the goal. A major playmaker in the various approaches to reaching the goal is the issue of proper diagnosis. Various diagnostic techniques were adopted in different regions and geographical locations over the decades, and these have invariably produced diverse outcomes. In this review, we looked at the various approaches used in malaria diagnostics with a focus on methods favorably used during pre-elimination and elimination phases as well as in endemic regions. Microscopy, rapid diagnostic testing (RDT), loop-mediated isothermal amplification (LAMP), and polymerase chain reaction (PCR) are common methods applied depending on prevailing factors, each with its strengths and limitations. As the drive toward the elimination goal intensifies, the search for ideal, simple, fast, and reliable point-of-care diagnostic tools is needed more than ever before to be used in conjunction with a functional surveillance system supported by the ideal vaccine.

Indexed as

MalariaMalaria, FalciparumDiagnostic Tests, RoutineGoalsHumansMicroscopyMolecular Diagnostic TechniquesNucleic Acid Amplification TechniquesPolymerase Chain ReactionSensitivity and SpecificityDiagnosticsEliminationMalariaMicroscopyRDTSurveillanceVaccine

Identifiers

PMID35460369
PMCPMC9033523

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.