Evidence map›Paper›PMID 35460366›Full record

ReviewPediatric cardiology2022

Ebstein's Anomaly: From Fetus to Adult-Literature Review and Pathway for Patient Care.

Tristan K W Ramcharan, Donna A Goff, Christopher E Greenleaf, Suhair O Shebani, Jorge D Salazar, Antonio F Corno

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Tristan K W RamcharanDepartment of Cardiology, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK. tristanramcharan@doctors.org.uk.ORCID http://orcid.org/0000-0003-0197-0722
Donna A GoffMcGovern Medical School, Children's Heart Institute, University of Texas Health, Houston, TX, USA.
Christopher E GreenleafMcGovern Medical School, Children's Heart Institute, University of Texas Health, Houston, TX, USA.
Suhair O ShebaniEast Midlands Congenital Heart Centre, Glenfield Hospital, University Hospitals of Leicester, Leicester, UK.
Jorge D SalazarMcGovern Medical School, Children's Heart Institute, University of Texas Health, Houston, TX, USA.
Antonio F CornoMcGovern Medical School, Children's Heart Institute, University of Texas Health, Houston, TX, USA.
The University of Texas Health Science Center · USBirmingham Women’s and Children’s NHS Foundation Trust · GBGlenfield Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ebstein's anomaly, first described in 1866 by Dr William Ebstein, accounts for 0.3-0.5% of congenital heart defects and represents 40% of congenital tricuspid valve abnormalities. Ebstein's anomaly affects the development of the tricuspid valve with widely varying morphology and, therefore, clinical presentation. Associated congenital cardiac lesions tend to be found more often in younger patients and may even be the reason for presentation. Presentation can vary from the most extreme form in fetal life, to asymptomatic diagnosis late in adult life. The most symptomatic patients need intensive care support in the neonatal period. This article summarizes and analyzes the literature on Ebstein's anomaly and provides a framework for the investigation, management, and follow-up of these patients, whether they present via fetal detection or late in adult life. For each age group, the clinical presentation, required diagnostic investigations, natural history, and management are described. The surgical options available for patients with Ebstein's anomaly are detailed and analyzed, starting from the initial mono-leaflet repairs to the most recent cone repair and its modifications. The review also assesses the effects of pregnancy on the Ebstein's circulation, and vice versa, the effects of Ebstein's on pregnancy outcomes. Finally, two attached appendices are provided for a structured echocardiogram protocol and key information useful for comprehensive Multi-Disciplinary Team discussion.

Indexed as

Ebstein AnomalyHeart Defects, CongenitalAdultEchocardiographyFetusHumansInfant, NewbornPatient CareTricuspid ValveCone procedureEbstein’s anomalyTricuspid valve

Identifiers

PMID35460366
OpenAlexW4224277756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.