Evidence map›Paper›PMID 35460230›Full record

SynthesisEuropean heart journal. Quality of care & clinical outcomes2022

Transradial versus transfemoral approach for percutaneous coronary intervention in patients with ST-elevation myocardial infarction complicated by cardiogenic shock: a systematic review and meta-analysis.

Muhammad Junaid Ahsan, Soban Ahmad, Azka Latif, Noman Lateef, Mohammad Zoraiz Ahsan, Waiel Abusnina, Sandeep Nathan, S Elissa Altin, Dhaval S Kolte, John C Messenger and 2 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in European heart journal. Quality of care & clinical outcomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Article
  6. Development of the first Iranian clinical practice guidelines for the diagnosis, treatment, and secondary prevention of acute coronary syndrome.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Muhammad Junaid AhsanDivision of Cardiovascular Medicine, Iowa Heart Center, Des Moines, IA, USA.ORCID 0000-0002-2472-9379
Soban AhmadDepartment of Internal Medicine, East Carolina University, Greenville, NC, USA.
Azka LatifDivision of Cardiovascular Medicine, Creighton University, Omaha, NE, USA.
Noman LateefDivision of Cardiovascular Medicine, University of Nebraska Medical Center, Omaha, NE, USA.
Mohammad Zoraiz AhsanDepartment of Internal Medicine, Fatima Memorial Hospital, Pakistan.
Waiel AbusninaDivision of Cardiovascular Medicine, Creighton University, Omaha, NE, USA.
Sandeep NathanDivision of Cardiovascular Medicine, University of Chicago, Chicago, IL, USA.
S Elissa AltinDivision of Cardiovascular Medicine, Yale University, New Haven, CT, USA.
Dhaval S KolteDivision of Cardiovascular Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
John C MessengerDivision of Cardiology Medicine, University of Colorado, Aurora, CO, USA.
Mark TannenbaumDivision of Cardiovascular Medicine, Iowa Heart Center, Des Moines, IA, USA.
Andrew M GoldsweigDivision of Cardiovascular Medicine, University of Nebraska Medical Center, Omaha, NE, USA.ORCID 0000-0003-2952-7837

Funding

Tracking and Evaluation CoreU54GM115458 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI GUDA, CHITTIBABU · 2016 to 2025
$42.8M
NIGMS NIH HHS U54 GM115458
6 · The paper itself

Abstract

backgroundIn ST-elevation myocardial infarction (STEMI), transradial access (TRA) for percutaneous coronary intervention (PCI) is associated with less bleeding and mortality than transfemoral access (TFA). However, patients in cardiogenic shock (CS) are more often treated via TFA. The aim of this meta-analysis is to compare the safety and efficacy of TRA vs. TFA in CS.

methodsSystematic review was performed querying PubMed, Google Scholar, Cochrane, and clinicaltrials.gov for studies comparing TRA to TFA in PCI for CS. Outcomes included in-hospital, 30-day and ≥1-year mortality, major and access site bleeding, TIMI3 (thrombolytics in myocardial infarction) flow, procedural success, fluoroscopy time, and contrast volume. Risk ratios (RRs) and 95% confidence intervals (CIs) were calculated using random effects models.

resultsSix prospective and eight retrospective studies (TRA, n = 8032; TFA, n = 23 031) were identified. TRA was associated with lower in-hospital (RR 0.59, 95% CI 0.52-0.66, P < 0.0001), 30-day and ≥1-year mortality, as well as less in-hospital major (RR 0.41, 0.31-0.56, P < 0.001) and access site bleeding (RR 0.42, 0.23-0.77, P = 0.005). There were no statistically significant differences in post-PCI coronary flow grade, procedural success, fluoroscopy time, and contrast volume between TRA vs. TFA.

conclusionsIn PCI for STEMI with CS, TRA is associated with significantly lower mortality and bleeding complications than TFA while achieving similar TIMI3 flow and procedural success rates.

Indexed as

Catheterization, PeripheralPercutaneous Coronary InterventionST Elevation Myocardial InfarctionFemoral ArteryHemorrhageHumansProspective StudiesRadial ArteryRetrospective StudiesRisk FactorsShock, CardiogenicTreatment Outcome

Identifiers

PMID35460230
PMCPMC9442849

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.