Evidence map›Paper›PMID 35460163›Full record

Trial reportBJOG : an international journal of obstetrics and gynaecology2022

Cost-effectiveness of an app-based treatment for urinary incontinence in comparison with care-as-usual in Dutch general practice: a pragmatic randomised controlled trial over 12 months.

Anne M M Loohuis, Henk Van Der Worp, Nienke J Wessels, Janny H Dekker, Marijke C Ph Slieker-Ten Hove, Marjolein Y Berger, Karin M Vermeulen, Marco H Blanker

Registry-linked trialOpen access · hybridAbstract readPragmatic Clinical TrialRandomized Controlled TrialEquivalence Trial
In one paragraph

Trial report in BJOG : an international journal of obstetrics and gynaecology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06896812 (A Pilot Study on App-based Treatment Combining Physical Exercise, Graded Activity, and Pain Journaling for Patients with Spinal Complaints), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06896812 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

A Pilot Study on App-based Treatment Combining Physical Exercise, Graded Activity, and Pain Journaling for Patients with Spinal Complaints

TypeinterventionalSponsorZuyderland Medisch CentrumRan2025 to 2025Enrolled30ConditionsBack Pain, Spinal Disease, Spinal ConditionArmsThe app-based treatment consists of a combination of physical exercise, graded activity, and pain journaling.
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Review
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Anne M M LoohuisDepartment of General Practice and Elderly Care Medicine, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0001-6582-1502
Henk Van Der WorpDepartment of General Practice and Elderly Care Medicine, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0001-5545-4155
Nienke J WesselsDepartment of General Practice and Elderly Care Medicine, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0002-1153-8709
Janny H DekkerDepartment of General Practice and Elderly Care Medicine, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0001-5005-9324
Marijke C Ph Slieker-Ten HoveProfundum Institute, Education and Research, Dordrecht, The Netherlands.ORCID 0000-0001-9516-8372
Marjolein Y BergerDepartment of General Practice and Elderly Care Medicine, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0001-6774-5961
Karin M VermeulenDepartment of Epidemiology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0001-9257-2791
Marco H BlankerDepartment of General Practice and Elderly Care Medicine, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0002-1086-8730
University Medical Center Groningen · NL

Funding

P.W. Boer FoundationZonMw, the Dutch Organisation for Health Research and Development 837001508
6 · The paper itself

Abstract

objectiveTo assess the cost-effectiveness of app-based treatment for female stress, urgency or mixed urinary incontinence (UI) compared with care-as-usual in Dutch primary care.

designA pragmatic, randomised controlled, superiority trial.

settingPrimary care in the Netherlands from 2015 to 2018, follow-up at 12 months. POPULATION: Women with ≥2 UI-episodes per week, access to mobile apps, wanting treatment.

methodsThe standalone app included conservative management for UI with motivation aids (e.g. reminders). Care-as-usual delivered according to the Dutch GP guideline for UI.

main outcome measuresCosts and cost-effectiveness and -utility were assessed from a societal perspective, based on incontinence impact adjusted life years (IIALYs), quality adjusted life years (QALYs) and medical, non-medical and productivity costs. Information on costs was obtained with the iMCQ and iPCQ questionnaires (medical consumption and productivity cost questionnaires).

resultsIn all, 262 women were andomised equally to app or care-as-usual; 89 (68%) and 83 (63%) attended follow-up, respectively. Costs were lower for app-based treatment with € -161 (95% confidence interval [CI -180 to -151) per year. Cost-effectiveness showed small mean differences in effect for IIALY (0.04) and QALY (-0.03) and thus larger incremental cost-effectiveness ratios (ICER: -€3696) and incremental cost-utility ratios (ICUR: €6379).

conclusionApp-based treatment is a cost-effective alternative to care-as-usual for women with UI in Dutch primary care. TWEETABLE ABSTRACT: App-treatment for female urinary incontinence cost-effective compared to care-as-usual in general practice after 12 months.

Indexed as

General PracticeMobile ApplicationsUrinary IncontinenceCost-Benefit AnalysisFemaleHumansQuality-Adjusted Life YearsQuality of Lifeappcost-effectivenesseHealthgeneral practicelong-termpragmaticprimary careself-managementurinary incontinence

Identifiers

PMID35460163
PMCPMC9545277
OpenAlexW4224309146

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.