Evidence map›Paper›PMID 35460050›Full record

ArticleSleep & breathing = Schlaf & Atmung2023

Relationship between severity of obstructive sleep apnea and benign prostatic hyperplasia.

Jie-Feng Huang, Ning Shen, Jian-Ming Zhao, Meng-Lan Chen, Bi-Ying Wang, Gong-Ping Chen

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07058038 (Association of Nocturnal Hypoxemia and Benign Prostatic Hyperplasia in Patients With Obstructive Sleep Apnea), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07058038 completednot on this map

Association of Nocturnal Hypoxemia and Benign Prostatic Hyperplasia in Patients With Obstructive Sleep Apnea

TypeobservationalSponsorMansoura UniversityRan2023 to 2024Enrolled91ConditionsBenign Prostate Hypertrophy(BPH), Obstructive Sleep Apnea( OSA)
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Risk factors for benign prostatic hyperplasia: a comprehensive review.Revista da Associacao Medica Brasileira (1992) · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jie-Feng Huang *Fujian Provincial Sleep-Disordered Breathing Clinic Center, Institute of Respiratory Disease, Fujian Medical University, NO 20, Chazhong Road, Taijiang District, Fuzhou, Fujian Province, 350005, People's Republic of China.
Ning Shen *Fujian Provincial Sleep-Disordered Breathing Clinic Center, Institute of Respiratory Disease, Fujian Medical University, NO 20, Chazhong Road, Taijiang District, Fuzhou, Fujian Province, 350005, People's Republic of China.
Jian-Ming Zhao *Fujian Provincial Sleep-Disordered Breathing Clinic Center, Institute of Respiratory Disease, Fujian Medical University, NO 20, Chazhong Road, Taijiang District, Fuzhou, Fujian Province, 350005, People's Republic of China.
Meng-Lan ChenFujian Provincial Sleep-Disordered Breathing Clinic Center, Institute of Respiratory Disease, Fujian Medical University, NO 20, Chazhong Road, Taijiang District, Fuzhou, Fujian Province, 350005, People's Republic of China.
Bi-Ying WangFujian Provincial Sleep-Disordered Breathing Clinic Center, Institute of Respiratory Disease, Fujian Medical University, NO 20, Chazhong Road, Taijiang District, Fuzhou, Fujian Province, 350005, People's Republic of China.
Gong-Ping ChenFujian Provincial Sleep-Disordered Breathing Clinic Center, Institute of Respiratory Disease, Fujian Medical University, NO 20, Chazhong Road, Taijiang District, Fuzhou, Fujian Province, 350005, People's Republic of China. cgp2389@126.com.ORCID 0000-0002-8566-0416
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe cause of benign prostatic hyperplasia (BPH) is controversial, local hypoxia and inflammation being the main two possibilities proposed. The aim of this study was to evaluate the relationship between obstructive sleep apnea (OSA) and BPH.

methodsThe study cohort comprised men from January 2016 to December 2020 in our Sleep Center. These patients were classified into four groups (no, mild, moderate, severe OSA) by apnea-hypopnea indexes (AHI). Logistic regression was used to identify independent risk factors for BPH, after which participants were stratified into younger (age ≤ 40 years) and older groups (age > 40 years) for further analysis.

resultsThe study cohort comprised 467 patients including 135 younger subjects and 332 older subjects. The prevalence of BPH in the above listed AHI categories was 37.5%, 55.0%, 62.9%, and 52.3%, respectively (p = 0.075). Logistic regression analysis of all patients identified age as a risk factor for BPH (p < 0.001). Stratified analysis according to AHI category found a prevalence of BPH of 0.0%, 13.0%, 33.3%, and 43.9%, respectively, in younger group (p = 0.006), and 52.2%, 71.9%, 71.1%, and 56.3%, respectively, in older group (p = 0.038). Logistic regression analysis found age and AHI were independent risk factors for BPH in younger group (both p < 0.05), whereas only age was identified as a risk factor for BPH in older group (p < 0.001).

conclusionsAge is an independent risk factor for BPH in men with OSA. AHI is also an independent risk factor for BPH in younger men, suggesting that OSA may affect development of BPH in younger men.

Indexed as

Prostatic HyperplasiaSleep Apnea, ObstructiveAdultAgedHumansLogistic ModelsMalePrevalenceRisk FactorsAgeBenign prostatic hyperplasiaObstructive sleep apneaYoung men

Identifiers

PMID35460050
OpenAlexW4224218355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.