Evidence map›Paper›PMID 35459911›Full record

Trial reportEuropean journal of clinical nutrition2022

Circulatory amino acid responses to milk consumption in dairy and lactose intolerant individuals.

Utpal Kumar Prodhan, Amber Marie Milan, Aahana Shrestha, Mark Hedley Vickers, David Cameron-Smith, Matthew Philip Greig Barnett

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of clinical nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Utpal Kumar ProdhanLiggins Institute, The University of Auckland, 85 Park Road, Grafton, Private Bag 92019, Auckland, 1023, New Zealand.ORCID 0000-0002-5208-1864
Amber Marie MilanLiggins Institute, The University of Auckland, 85 Park Road, Grafton, Private Bag 92019, Auckland, 1023, New Zealand.
Aahana ShresthaLiggins Institute, The University of Auckland, 85 Park Road, Grafton, Private Bag 92019, Auckland, 1023, New Zealand.ORCID 0000-0003-2162-6494
Mark Hedley VickersLiggins Institute, The University of Auckland, 85 Park Road, Grafton, Private Bag 92019, Auckland, 1023, New Zealand.
David Cameron-SmithLiggins Institute, The University of Auckland, 85 Park Road, Grafton, Private Bag 92019, Auckland, 1023, New Zealand.
Matthew Philip Greig BarnettThe Riddet Institute, Palmerston North, 4442, New Zealand. matthew.barnett@agresearch.co.nz.ORCID 0000-0002-5186-5579
University of Auckland · NZAgResearch · NZStatistics New Zealand · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesSelf-reported digestive intolerance to dairy foods is common. As dairy can be an important source of dietary protein, this study aimed to identify whether milk protein digestion is compromised in individuals with digestive intolerance. SUBJECTS/

methodsAdult women (n = 40) were enroled in this double-blinded, randomised cross-over trial, with digestive symptoms characterised using a lactose challenge and self-reported digestive symptom questionnaire. Participants were classified as either lactose intolerant (LI, n = 10), non-lactose dairy intolerant (NLDI, n = 20) or dairy tolerant (DT, n = 10). In a randomised sequence, participants consumed three different kinds of milk (750 ml); conventional milk (CON), a2 Milk™ (A2M), and lactose-free conventional milk (LF-CON). Circulatory plasma amino acid (AA) concentrations were measured at baseline and every 30 min until 3 h post-ingestion.

resultsIn all participants across all milk types, plasma AA concentrations (AUC

conclusionMilk protein digestion, as determined by circulatory AAs, is largely unaffected by dairy- and lactose- intolerances.

Indexed as

Amino AcidsLactose IntoleranceAdultAnimalsDietary ProteinsFemaleHumansLysineMilkAmino AcidsDietary ProteinsLysine

Identifiers

PMID35459911
PMCPMC9550627
OpenAlexW4224220281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.