Evidence map›Paper›PMID 35459652›Full record

ArticleBMJ case reports2022

Acute herpes zoster radiculopathy mimicking cervical radiculopathy after ChAdOx1 nCoV-19/AZD1222 vaccination.

Andrew Dermawan, Matthew Jun Min Ting, Thomas Chemmanam, Chok Lui

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Andrew DermawanGeneral Medicine, Royal Perth Hospital, Perth, Western Australia, Australia andrew.dermawan@health.wa.gov.au.ORCID http://orcid.org/0000-0002-0172-7872
Matthew Jun Min TingGeriatric department, St John of God Midland Public and Private Hospitals, Midland, Western Australia, Australia.ORCID http://orcid.org/0000-0003-2505-9423
Thomas ChemmanamNeurology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.ORCID http://orcid.org/0000-0002-3327-6076
Chok LuiGeriatric department, St John of God Midland Public and Private Hospitals, Midland, Western Australia, Australia.
St John of God Hospital · AURoyal Perth Hospital · AUSir Charles Gairdner Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report describes an 84-year-old man who presented with 3 weeks of gradually worsening right arm weakness associated with a painful vesicular rash across his arm. This occurred 3 days after his first dose of the ChAdOx1 nCoV-19/AZD1222 (University of Oxford, AstraZeneca and the Serum Institute of India) vaccine. The diagnosis was complicated by the presence of right C5-C6 foraminal stenosis compressing on the C6 nerve root sheath on non-contrast MRI, leading to an initial diagnosis of cervical radiculopathy. However, a positive varicella zoster virus-PCR test and findings of abnormal contrast enhancement of his right C5-C7 nerve roots on gadolinium-enhanced MRI resulted in a revision of his diagnosis to zoster radiculopathy. He was subsequently commenced on oral valacilovir and made significant recovery. This report aims to highlight the diagnostic dilemma between cervical radiculopathy secondary to spondylosis and zoster radiculopathy and how an erroneous diagnosis could result in inappropriate, aggressive surgical intervention and delayed treatment with antiviral therapy.

Indexed as

Herpes ZosterRadiculopathyAged, 80 and overChAdOx1 nCoV-19Herpesvirus 3, HumanHumansMaleVaccinationChAdOx1 nCoV-19COVID-19Peripheral nerve diseaseUnwanted effects / adverse reactionsVaccination/immunisation

Identifiers

PMID35459652
PMCPMC9036357
OpenAlexW4224317100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.