Evidence map›Paper›PMID 35459274›Full record

ArticleNature communications2022

Enabling reactive microscopy with MicroMator.

Zachary R Fox, Steven Fletcher, Achille Fraisse, Chetan Aditya, Sebastián Sosa-Carrillo, Julienne Petit, Sébastien Gilles, François Bertaux, Jakob Ruess, Gregory Batt

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
8.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
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  11. Live-cell imaging powered by computation.Nature reviews. Molecular cell biology · 2024
    Review
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  14. Live-cell imaging in the deep learning era.Current opinion in cell biology · 2023
    Review
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Zachary R Fox *Inria Paris, 2 rue Simone Iff, 75012, Paris, France.ORCID 0000-0003-0138-2867
Steven Fletcher *Inria Paris, 2 rue Simone Iff, 75012, Paris, France.
Achille FraisseInria Paris, 2 rue Simone Iff, 75012, Paris, France.
Chetan AdityaInria Paris, 2 rue Simone Iff, 75012, Paris, France.ORCID 0000-0002-2872-580X
Sebastián Sosa-CarrilloInria Paris, 2 rue Simone Iff, 75012, Paris, France.
Julienne PetitStructural Microbiology Unit, Institut Pasteur, CNRS UMR 3528, Université de Paris, F-75015, Paris, France.
Sébastien GillesInria Saclay-Ile-de-France, 1 rue H. d'Estienne d'Orves, 91120, Palaiseau, France.
François BertauxInria Paris, 2 rue Simone Iff, 75012, Paris, France.ORCID 0000-0002-0942-6142
Jakob RuessInria Paris, 2 rue Simone Iff, 75012, Paris, France.
Gregory BattInria Paris, 2 rue Simone Iff, 75012, Paris, France. gregory.batt@inria.fr.ORCID 0000-0003-1697-139X
Institut national de recherche en sciences et technologies du numérique · FRCentre Inria de Saclay · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microscopy image analysis has recently made enormous progress both in terms of accuracy and speed thanks to machine learning methods and improved computational resources. This greatly facilitates the online adaptation of microscopy experimental plans using real-time information of the observed systems and their environments. Applications in which reactiveness is needed are multifarious. Here we report MicroMator, an open and flexible software for defining and driving reactive microscopy experiments. It provides a Python software environment and an extensible set of modules that greatly facilitate the definition of events with triggers and effects interacting with the experiment. We provide a pedagogic example performing dynamic adaptation of fluorescence illumination on bacteria, and demonstrate MicroMator's potential via two challenging case studies in yeast to single-cell control and single-cell recombination, both requiring real-time tracking and light targeting at the single-cell level.

Indexed as

MicroscopySoftwareImage Processing, Computer-AssistedMachine LearningSaccharomyces cerevisiae

Identifiers

PMID35459274
PMCPMC9033843
OpenAlexW4224214682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.