Evidence map›Paper›PMID 35459225›Full record

ArticleNPJ vaccines2022

An adjuvanted zoster vaccine elicits potent cellular immune responses in mice without QS21.

Hyo Jung Nam, Sung Jun Hong, Ara Lee, Jiyeon Kim, Sangho Lee, Corey Casper, Darrick Carter, Steven G Reed, George Simeon, Eui-Cheol Shin

Open access · goldAbstract read
In one paragraph

Article in NPJ vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Hyo Jung NamLaboratory of Immunology and Infectious Diseases, Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.ORCID http://orcid.org/0000-0003-0344-6166
Sung Jun HongMOGAM Institute for Biomedical Research, Gyeonggi-do, Republic of Korea.
Ara LeeMOGAM Institute for Biomedical Research, Gyeonggi-do, Republic of Korea.
Jiyeon KimGC Pharma, Gyeonggi-do, Republic of Korea.
Sangho LeeGC Pharma, Gyeonggi-do, Republic of Korea.
Corey CasperInfectious Disease Research Institute, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-3609-661X
Darrick CarterPAI Life Sciences Inc., Seattle, WA, USA.
Steven G ReedInfectious Disease Research Institute, Seattle, WA, USA.
George SimeonCUREVO Vaccine, Seattle, WA, USA.
Eui-Cheol ShinLaboratory of Immunology and Infectious Diseases, Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea. ecshin@kaist.ac.kr.ORCID http://orcid.org/0000-0002-6308-9503
Infectious Disease Research Institute · USKorea Advanced Institute of Science and Technology · KRCancer Research And Biostatistics · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes zoster (HZ) is caused by reactivation of latent varicella-zoster virus (VZV) when VZV-specific cellular immunity is insufficient to control reactivation. Currently, Shingrix, which contains the VZV gE protein and GSK's AS01

Identifiers

PMID35459225
PMCPMC9033770
OpenAlexW4224293651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.