ArticleSensors (Basel, Switzerland)2022
Applications of Laser-Induced Fluorescence in Medicine.
Article in Sensors (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
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- Fluorescence lifetime imaging of 5-ALA-induced PpIX and autofluorescence for detecting infiltrating glioblastoma margins in patients.Biomedical optics express · 2026Article
- Transforming Cancer Diagnosis and Therapy Through Fluorescent Hydrogels: A Review.Advanced healthcare materials · 2026Review
- Application of Wood's Lamp in Dermatological and Dental Photodiagnostics.Sensors (Basel, Switzerland) · 2025Article
- Assessment of Emergency Spacers Versus Traditional Spacers, An In-Vitro Model for Aerosol Delivery.AAPS PharmSciTech · 2025Article
- Differentiating between normal and inflammatory blood serum samples using spectrochemical analytical techniques and chemometrics.Analytical and bioanalytical chemistry · 2025Article
- The research progress of label-free optical imaging technology in intraoperative real-time navigation of parathyroid glands.Lasers in medical science · 2025Review
- Biomedical Sensors for Functional Mapping: Techniques, Methods, Experimental and Medical Applications.Sensors (Basel, Switzerland) · 2023Article
- Fluorescence Methods for the Detection of Bioaerosols in Their Civil and Military Applications.Sensors (Basel, Switzerland) · 2023Review
- Study of laser fluorescence spectroscopy in livers of rats with hypothermic ischemia.Acta cirurgica brasileira · 2023Article
- Optical Characterization of Biological Tissues Based on Fluorescence, Absorption, and Scattering Properties.Diagnostics (Basel, Switzerland) · 2022Article
- Label-free fluorescence lifetime imaging for real-time guidance of stereotactic biopsy: A feasibility study in brain cancer patients.Neuro-oncology advancesArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fluorescence is the most sensitive spectroscopic method of analysis and fluorescence methods. However, classical analysis requires sampling. There are new needs for real-time analyses of biological materials, without the need for sampling. This article presents examples of proprietary applications of laser-induced fluorescence (LIF) in medicine with such methods. A classic example is the analysis of photosensitizers using the photodynamic treatment method (PDT). The level and kinetics of accumulation and excretion of sensitizers in the body are examined, as well as the optimal exposure time after the application of compounds. The LIF method is also used to analyze endogenous fluorophores; it has been used to detect neoplasms, e.g., lung cancer or gynecological and dermatological diseases. Furthermore, it is used for the diagnosis of early stages of tooth decay or detection of fungi. The article will present the construction of sensors based on the LIF method-fiber laser spectrometers and investigated fluorescence spectra in individual applications. Examples of fluorescence imaging, e.g., dermatological, and dental diagnostics and measuring systems will be presented. The advantage of the method is it has greater sensitivity and easily detects lesions early compared to the methods used in observing the material in reflected light.
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Registered trials
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