Mechanochemical Dimerization of Aldoximes to Furoxans.

Run-Kai Fang, Kuan Chen, Chuang Niu, Guan-Wu Wang

Open access · goldAbstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.1field-weighted citation impact, top 52% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Run-Kai FangHefei National Laboratory for Physical Sciences, Microscale and Department of Chemistry, University of Science and Technology of China, Hefei 230026, China.

Kuan ChenHefei National Laboratory for Physical Sciences, Microscale and Department of Chemistry, University of Science and Technology of China, Hefei 230026, China.

Chuang NiuHefei National Laboratory for Physical Sciences, Microscale and Department of Chemistry, University of Science and Technology of China, Hefei 230026, China.

Guan-Wu WangHefei National Laboratory for Physical Sciences, Microscale and Department of Chemistry, University of Science and Technology of China, Hefei 230026, China.ORCID 0000-0001-9287-532X

University of Science and Technology of China · CN

Funding

National Natural Science Foundation of China 21372211

6 · The paper itself

Abstract

Solvent-free mechanical milling is a new, environmentally friendly and cost-effective technology that is now widely used in the field of organic synthesis. The mechanochemical solvent-free synthesis of furoxans from aldoximes was achieved through dimerization of the in situ generated nitrile oxides in the presence of sodium chloride, Oxone and a base. A variety of furoxans was obtained with up to a 92% yield. The present protocol has the advantages of high reaction efficiency and mild reaction conditions.

Indexed as

OxadiazolesOximesChemistry Techniques, SyntheticDimerizationSolventsfuroxansOxadiazolesOximesSolventsaldoximesdimerizationfuroxansmechanochemistrynitrile oxides

Identifiers

PMID35458802

DOI10.3390/molecules27082604

PMCPMC9027020

OpenAlexW4224254994

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.