Evidence map›Paper›PMID 35458684›Full record

ArticleMolecules (Basel, Switzerland)2022

Eriodictyol and Homoeriodictyol Improve Memory Impairment in Aβ

Pengli Guo, Mengnan Zeng, Shengchao Wang, Bing Cao, Meng Liu, Yuhan Zhang, Jufang Jia, Qinqin Zhang, Beibei Zhang, Ru Wang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Process Optimization and Flavor Analysis ofFoods (Basel, Switzerland) · 2026
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  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Optimized De Novo Eriodictyol Biosynthesis inInternational journal of molecular sciences · 2023
    Article
  12. Article
  13. [Anti-inflammatory mechanism ofNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023
    Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Pengli GuoCollege of Pharmacy, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou 450046, China.
Mengnan ZengCollege of Pharmacy, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou 450046, China.
Shengchao WangCollege of Pharmacy, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou 450046, China.
Bing CaoCollege of Pharmacy, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou 450046, China.
Meng LiuCollege of Pharmacy, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou 450046, China.
Yuhan ZhangCollege of Pharmacy, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou 450046, China.
Jufang JiaCollege of Pharmacy, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou 450046, China.
Qinqin ZhangCollege of Pharmacy, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou 450046, China.
Beibei ZhangCollege of Pharmacy, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou 450046, China.
Ru WangCollege of Pharmacy, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou 450046, China.
Xiaoke ZhengCollege of Pharmacy, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou 450046, China.
Weisheng FengCollege of Pharmacy, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou 450046, China.
First Affiliated Hospital of Henan University · CNHenan Bioengineering Technology Research Center · CN

Funding

Doctoral Fund of Henan University of Chinese Medicine RSBSJJ2019-10Henan province high-level personnel special support "ZhongY uan One Thousand People Plan," ZYQR201810080Henan Province Traditional Chinese Medicine Scientific Research Project 20-212Y2152The Major Science and Technology Projects in Henan Province: Study on the key technology for quality control and the key characteristics of Rehmannia glutinosa, Dioscorea opposita Thunb. and Achyranthes bidentata Blume from Henan Province 171100310500The National Key Research and Development Project 2019YFC1708802, 2017YFC1702800
6 · The paper itself

Abstract

(1) Alzheimer's disease (AD) is a neurodegenerative disorder, and it is now widely accepted that neuroinflammation plays a key role in its pathogenesis. Eriodictyol (Eri) and homoeriodictyol (Hom), dihydroflavonoids extracted from a variety of plants, have been confirmed to display a relationship with neuroprotection. (2) Methods: An AD mouse model was constructed by intracerebroventricular (ICV) injection of the Aβ

Indexed as

Alzheimer DiseaseInflammasomesAnimalsChromatography, LiquidDisease Models, AnimalFlavanonesFlavonesLipopolysaccharidesMemory DisordersMiceMice, Inbred C57BLMicrogliaNigericinNLR Family, Pyrin Domain-Containing 3 ProteinTandem Mass SpectrometryeriodictyolFlavanonesFlavoneshomoeriodictyolInflammasomesLipopolysaccharidesNigericinNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseAlzheimer’s diseaseAβ25–35eriodictyolhomoeriodictyolNLRP3 inflammasome

Identifiers

PMID35458684
PMCPMC9025671
OpenAlexW4224315620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.