Evidence map›Paper›PMID 35458647›Full record

ArticleMolecules (Basel, Switzerland)2022

Media Supplementation with Mannitol and Biotin Enhances Squalene Production of

M Kashif Ali, Biswarup Sen, Yaodong He, Mohan Bai, Guangyi Wang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
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  5. Article
  6. Optimization of Squalene Production byMolecules (Basel, Switzerland) · 2025
    Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

M Kashif AliCenter of Marine Environmental Ecology, School of Environmental Science and Engineering, Tianjin University, Tianjin 300072, China.
Biswarup SenCenter of Marine Environmental Ecology, School of Environmental Science and Engineering, Tianjin University, Tianjin 300072, China.ORCID 0000-0002-6712-6244
Yaodong HeCenter of Marine Environmental Ecology, School of Environmental Science and Engineering, Tianjin University, Tianjin 300072, China.ORCID 0000-0003-0961-4079
Mohan BaiCollege of Life Science, Zhejiang University, Hangzhou 310058, China.
Guangyi WangCenter of Marine Environmental Ecology, School of Environmental Science and Engineering, Tianjin University, Tianjin 300072, China.ORCID 0000-0003-3439-7117
Tianjin University · CNZhejiang University · CN

Funding

National Natural Science Foundation of China 32170063Think Tank United Foundation of Qingdao Marine Engineering and Technology 201707071001
6 · The paper itself

Abstract

Media supplementation with exogenous chemicals is known to stimulate the accumulation of important lipids produced by microalgae and thraustochytrids. However, the roles of exogenous chemicals in promoting and preserving the terpenoids pool of thraustochytrids have been rarely investigated. Here, we realized the effects of two media supplements-mannitol and biotin-on the biomass and squalene production by a thraustochytrid strain (

Indexed as

SqualeneStramenopilesAntioxidantsBiotinCulture MediaDietary SupplementsFermentationGlucoseMannitolAntioxidantsBiotinCulture MediaGlucoseMannitolSqualenebiotinmannitoloxidative stresssqualenesupplementationthraustochytrids

Identifiers

PMID35458647
PMCPMC9029391
OpenAlexW4223499661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.