Evidence map›Paper›PMID 35458621›Full record

ArticleMolecules (Basel, Switzerland)2022

Formulation and Testing of Antioxidant and Protective Effect of Hyalurosomes Loading Extract Rich in Rosmarinic Acid Biotechnologically Produced from

Matteo Perra, Laura Fancello, Ines Castangia, Mohamad Allaw, Elvira Escribano-Ferrer, José Esteban Peris, Iris Usach, Maria Letizia Manca, Ivanka K Koycheva, Milen I Georgiev and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Trial
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  5. Article
  6. Liposomal Delivery of a BiotechnologicalAntioxidants (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Matteo PerraDepartment of Scienze della Vita e dell'Ambiente, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0002-9906-990X
Laura FancelloDepartment of Scienze della Vita e dell'Ambiente, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0002-5331-2548
Ines CastangiaDepartment of Scienze della Vita e dell'Ambiente, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0002-3100-8107
Mohamad AllawDepartment of Scienze della Vita e dell'Ambiente, University of Cagliari, 09124 Cagliari, Italy.
Elvira Escribano-FerrerBiopharmaceutics and Pharmacokinetics Unit, Institute for Nanoscience and Nanotechnology, University of Barcelona, 08007 Barcelona, Spain.
José Esteban PerisDepartment of Pharmacy and Pharmaceutical Technology and Parasitology, University of Valencia, 46100 Valencia, Spain.
Iris UsachDepartment of Pharmacy and Pharmaceutical Technology and Parasitology, University of Valencia, 46100 Valencia, Spain.ORCID 0000-0002-5786-5668
Maria Letizia MancaDepartment of Scienze della Vita e dell'Ambiente, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0002-3787-257X
Ivanka K KoychevaLaboratory of Metabolomics, Department of Biotechnology, Institute of Microbiology, Bulgarian Academy of Sciences, 4002 Plovdiv, Bulgaria.
Milen I GeorgievLaboratory of Metabolomics, Department of Biotechnology, Institute of Microbiology, Bulgarian Academy of Sciences, 4002 Plovdiv, Bulgaria.ORCID 0000-0001-5248-6135
Maria ManconiDepartment of Scienze della Vita e dell'Ambiente, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0003-4818-2344
University of Cagliari · ITBulgarian Academy of Sciences · BGUniversitat de València · ESUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Culture of plant cells or tissues is a scalable, sustainable, and environmentally friendly approach to obtain extracts and secondary metabolites of uniform quality that can be continuously supplied in controlled conditions, independent of geographical and seasonal variations, environmental factors, and negative biological influences. In addition, tissues and cells can be extracted/obtained from the by-products of other industrial cultivations such as that of

Indexed as

LavandulaAntioxidantsCinnamatesDepsidesPlant ExtractsRosmarinic AcidAntioxidantsCinnamatesDepsidesPlant ExtractsRosmarinic Acidbiotechnologically produced extractfibroblastshyalurosomeslamellar vesiclesLavandula angustifolianatural antioxidant

Identifiers

PMID35458621
PMCPMC9029676
OpenAlexW4224214756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.