Evidence map›Paper›PMID 35458573›Full record

ArticleViruses2022

Evaluation of Molecular Test for the Discrimination of "Naked" DNA from Infectious Parvovirus B19 Particles in Serum and Bone Marrow Samples.

Arthur Daniel Rocha Alves, Barbara Barbosa Langella, Mariana Magaldi de Souza Lima, Wagner Luís da Costa Nunes Pimentel Coelho, Rita de Cássia Nasser Cubel Garcia, Claudete Aparecida Araújo Cardoso, Renato Sergio Marchevsky, Marcelo Alves Pinto, Luciane Almeida Amado

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Arthur Daniel Rocha AlvesLaboratório de Desenvolvimento Tecnológico em Virologia, Instituto Oswaldo Cruz, FIOCRUZ, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-900, Brazil.
Barbara Barbosa LangellaLaboratório de Desenvolvimento Tecnológico em Virologia, Instituto Oswaldo Cruz, FIOCRUZ, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-900, Brazil.
Mariana Magaldi de Souza LimaLaboratório de Desenvolvimento Tecnológico em Virologia, Instituto Oswaldo Cruz, FIOCRUZ, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-900, Brazil.
Wagner Luís da Costa Nunes Pimentel CoelhoLaboratório de Desenvolvimento Tecnológico em Virologia, Instituto Oswaldo Cruz, FIOCRUZ, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-900, Brazil.
Rita de Cássia Nasser Cubel GarciaDepartamento de Microbiologia e Parasitologia, Instituto Biomédico, Universidade Federal Fluminense, Niterói, Rio de Janeiro 24210-230, Brazil.
Claudete Aparecida Araújo CardosoDepartamento Materno Infantil, Faculdade de Medicina, Universidade Federal Fluminense, Niterói, Rio de Janeiro 24033-900, Brazil.ORCID 0000-0002-7638-6814
Renato Sergio MarchevskyVice Diretoria de Qualidade, Instituto de Tecnologia em Imunobiológicos, FIOCRUZ, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-900, Brazil.
Marcelo Alves PintoLaboratório de Desenvolvimento Tecnológico em Virologia, Instituto Oswaldo Cruz, FIOCRUZ, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-900, Brazil.ORCID 0000-0003-3462-7277
Luciane Almeida AmadoLaboratório de Desenvolvimento Tecnológico em Virologia, Instituto Oswaldo Cruz, FIOCRUZ, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-900, Brazil.
Fundação Oswaldo Cruz · BRUniversidade Federal Fluminense · BRInstituto de Tecnologia e Pesquisa · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low levels of parvovirus B19 (B19V) DNA can be detected in the circulation and in different tissue of immunocompetent individuals for months or years, which has been linked to inflammatory diseases such as cardiomyopathy, rheumatoid arthritis, hepatitis, and vasculitis. However, the detection of B19V DNA does not necessarily imply that infectious virions are present. This study aimed to evaluate the method based on the Benzonase

Indexed as

Parvoviridae InfectionsParvovirus B19, HumanBone MarrowDNA, ViralHumansViremiaDNA, Viralacute infectionBenzonase®parvovirus B19persistent infectionviral DNA load

Identifiers

PMID35458573
PMCPMC9027101
OpenAlexW4224284970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.