Evidence map›Paper›PMID 35458560›Full record

ArticleViruses2022

Development of Dog Vaccination Strategies to Maintain Herd Immunity against Rabies.

Ahmed Lugelo, Katie Hampson, Elaine A Ferguson, Anna Czupryna, Machunde Bigambo, Christian Tetteh Duamor, Rudovick Kazwala, Paul C D Johnson, Felix Lankester

Abstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ahmed LugeloEnvironmental Health and Ecological Sciences Department, Ifakara Health Institute, Dar es Salaam P.O. Box 78373, Tanzania.ORCID 0000-0003-1722-4329
Katie HampsonBoyd Orr Centre for Population and Ecosystem Health, Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Graham Kerr Building, Glasgow G12 8QQ, UK.ORCID 0000-0001-5392-6884
Elaine A FergusonBoyd Orr Centre for Population and Ecosystem Health, Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Graham Kerr Building, Glasgow G12 8QQ, UK.ORCID 0000-0003-2010-765X
Anna CzuprynaBoyd Orr Centre for Population and Ecosystem Health, Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Graham Kerr Building, Glasgow G12 8QQ, UK.
Machunde BigamboGlobal Animal Health Tanzania, Arusha 1642, Tanzania.
Christian Tetteh DuamorDepartment of Global Health, Nelson Mandela African Institution of Science and Technology, Arusha P.O. Box 447, Tanzania.ORCID 0000-0001-8930-9060
Rudovick KazwalaDepartment of Veterinary Medicine and Public Health, Sokoine University of Agriculture, Morogoro P.O. Box 3105, Tanzania.
Paul C D JohnsonBoyd Orr Centre for Population and Ecosystem Health, Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Graham Kerr Building, Glasgow G12 8QQ, UK.ORCID 0000-0001-6663-7520
Felix LankesterGlobal Animal Health Tanzania, Arusha 1642, Tanzania.ORCID 0000-0002-0802-0693

Funding

Eliminating human rabies: impact of enhanced vaccination coverageR01AI141712 · NIAID · WASHINGTON STATE UNIVERSITY · PI LANKESTER, FELIX · 2019 to 2023
$2.3M
NIAID NIH HHS R01 AI141712NIH HHS R01AI141712Wellcome Trust 107753/A/15/Z & 207569/Z/17/ZWellcome Trust 207569/Z/17/Z
6 · The paper itself

Abstract

Human rabies can be prevented through mass dog vaccination campaigns; however, in rabies endemic countries, pulsed central point campaigns do not always achieve the recommended coverage of 70%. This study describes the development of a novel approach to sustain high coverage based on decentralized and continuous vaccination delivery. A rabies vaccination campaign was conducted across 12 wards in the Mara region, Tanzania to test this approach. Household surveys were used to obtain data on vaccination coverage as well as factors influencing dog vaccination. A total 17,571 dogs were vaccinated, 2654 using routine central point delivery and 14,917 dogs using one of three strategies of decentralized continuous vaccination. One month after the first vaccination campaign, coverage in areas receiving decentralized vaccinations was higher (64.1, 95% Confidence Intervals (CIs) 62.1-66%) than in areas receiving pulsed vaccinations (35.9%, 95% CIs 32.6-39.5%). Follow-up surveys 10 months later showed that vaccination coverage in areas receiving decentralized vaccinations remained on average over 60% (60.7%, 95% CIs 58.5-62.8%) and much higher than in villages receiving pulsed vaccinations where coverage was on average 32.1% (95% CIs 28.8-35.6%). We conclude that decentralized continuous dog vaccination strategies have the potential to improve vaccination coverage and maintain herd immunity against rabies.

Indexed as

Dog DiseasesRabiesRabies VaccinesAnimalsDogsImmunity, HerdVaccinationVaccination CoverageRabies Vaccinesdecentralized continuous vaccinationherd immunitymass dog vaccinationrabiesvaccination strategy

Identifiers

PMID35458560
PMCPMC9028497

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.