Evidence map›Paper›PMID 35458496›Full record

ArticleViruses2022

A Miniaturized Electrostatic Precipitator Respirator Effectively Removes Ambient SARS-CoV-2 Bioaerosols.

Rachel K Redmann, Brandon J Beddingfield, Skye Spencer, Nicole R Chirichella, Julian L Henley, Wes Hager, Chad J Roy

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rachel K RedmannInfectious Disease Aerobiology, Division of Microbiology, Tulane National Primate Research Center, Covington, LA 70433, USA.ORCID 0000-0002-8822-0707
Brandon J BeddingfieldInfectious Disease Aerobiology, Division of Microbiology, Tulane National Primate Research Center, Covington, LA 70433, USA.ORCID 0000-0002-9438-1304
Skye SpencerInfectious Disease Aerobiology, Division of Microbiology, Tulane National Primate Research Center, Covington, LA 70433, USA.ORCID 0000-0001-9570-9634
Nicole R ChirichellaInfectious Disease Aerobiology, Division of Microbiology, Tulane National Primate Research Center, Covington, LA 70433, USA.
Julian L HenleySection of Otolaryngology, Yale-New Haven Hospital, New Haven, CT 06520, USA.
Wes HagerPhase Three Product Development, Fort Collins, CO 80526, USA.
Chad J RoyInfectious Disease Aerobiology, Division of Microbiology, Tulane National Primate Research Center, Covington, LA 70433, USA.ORCID 0000-0002-1710-6974
Tulane University · USYale New Haven Hospital · US

Funding

Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
NIH HHS OD011104NIH HHS P51 OD011104
6 · The paper itself

Abstract

The inhalation of ambient SARS-CoV-2-containing bioaerosols leads to infection and pandemic airborne transmission in susceptible populations. Filter-based respirators effectively reduce exposure but complicate normal respiration through breathing zone pressure differentials; therefore, they are impractical for long-term use.

objectivesWe tested the comparative effectiveness of a prototyped miniaturized electrostatic precipitator (mEP) on a filter-based respirator (N95) via the removal of viral bioaerosols from a simulated, inspired air stream. MEASUREMENTS AND MAIN

resultsThe mEP respirator removed particles (96.5 ± 0.4%), approximating efficiencies of the N95 (96.9 ± 0.6%). The mEP respirator similarly decreased SARS-CoV-2 viral RNA (99.792%) when compared to N95 removal (99.942%), as a function of particle removal from the airstream distal to the breathing zone of each respirator.

conclusionsThe mEP respirator approximated the performance of a filter-based N95 respirator for particle removal and viral RNA as a constituent of the SARS-CoV-2 bioaerosols generated for this evaluation. In practice, the mEP respirator could provide equivalent protection from ambient infectious bioaerosols as the N95 respirator without undue pressure drop to the wearer, thereby facilitating its long-term use in an unobstructed breathing configuration.

Indexed as

COVID-19SARS-CoV-2HumansRNA, ViralStatic ElectricityVentilators, MechanicalRNA, Viralbioaerosolselectrostatic precipitationrespiratory protectionSARS-CoV-2

Identifiers

PMID35458496
PMCPMC9025737
OpenAlexW4224312427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.