Evidence map›Paper›PMID 35458489›Full record

ReviewViruses2022

Replicating Viral Vector-Based Vaccines for COVID-19: Potential Avenue in Vaccination Arena.

Vivek P Chavda, Rajashri Bezbaruah, Mansi Athalye, Palak K Parikh, Abu Sufiyan Chhipa, Snehal Patel, Vasso Apostolopoulos

Abstract readReview
In one paragraph

Review in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  8. COVID-19 vaccine triggered autoimmune hepatitis: case report.European journal of hospital pharmacy : science and practice · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vivek P ChavdaDepartment of Pharmaceutics and Pharmaceutical Technology, L. M. College of Pharmacy, Ahmedabad 380009, Gujarat, India.
Rajashri BezbaruahDepartment of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh 786004, Assam, India.
Mansi AthalyeDepartment of Pharmaceutics and Pharmaceutical Technology, L. M. College of Pharmacy, Ahmedabad 380009, Gujarat, India.
Palak K ParikhDepartment of Pharmaceutical Chemistry and Quality Assurance, L. M. College of Pharmacy, Ahmedabad 380009, Gujarat, India.
Abu Sufiyan ChhipaDepartment of Pharmacology, Institute of Pharmacy, Nirma University, Ahmedabad 382481, Gujarat, India.ORCID 0000-0003-1208-1162
Snehal PatelDepartment of Pharmacology, Institute of Pharmacy, Nirma University, Ahmedabad 382481, Gujarat, India.
Vasso ApostolopoulosInstitute for Health and Sport, Victoria University, Melbourne, VIC 3030, Australia.ORCID 0000-0001-6788-2771

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The "severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)" is the third member of human coronavirus (CoV) that is held accountable for the current "coronavirus disease 2019 (COVID-19)" pandemic. In the past two decades, the world has witnessed the emergence of two other similar CoVs, namely SARS-CoV in 2002 and MERS-CoV in 2013. The extent of spread of these earlier versions was relatively low in comparison to SARS-CoV-2. Despite having numerous reports inclined towards the zoonotic origin of the virus, one cannot simply sideline the fact that no animal originated CoV is thus far identified that is considered similar to the initial edition of SARS-CoV-2; however, under-sampling of the diverse variety of coronaviruses remains a concern. Vaccines are proved to be an effective tool for bringing the end to such a devastating pandemic. Many vaccine platforms are explored for the same but in this review paper, we will discuss the potential of replicating viral vectors as vaccine carriers for SARS-CoV-2.

Indexed as

COVID-19Viral VaccinesCOVID-19 VaccinesHumansSARS-CoV-2VaccinationCOVID-19 VaccinesViral VaccinesCOVID-19replicating viral vectorSARS-CoV-2vaccinevaccine efficacyviral vector-based vaccine

Identifiers

PMID35458489
PMCPMC9025561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.