Evidence map›Paper›PMID 35458388›Full record

ArticleViruses2022

Clinical, Laboratory, and Molecular Epidemiology of an Outbreak of Aseptic Meningitis Due to a Triple-Recombinant Echovirus in Ashburton, New Zealand.

Meik Dilcher, Julia C Howard, Simon C Dalton, Trevor Anderson, Richard T Clinghan, Anja M Werno

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Genetic Characteristics and Phylogeographic Dynamics of Echovirus.Journal of microbiology (Seoul, Korea) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Meik DilcherMicrobiology Department, Virology/Serology Section, Canterbury Health Laboratories, Christchurch 8011, New Zealand.ORCID 0000-0003-1737-6277
Julia C HowardMicrobiology Department, Virology/Serology Section, Canterbury Health Laboratories, Christchurch 8011, New Zealand.ORCID 0000-0003-1612-2136
Simon C DaltonDepartment of Infectious Diseases, Christchurch Hospital, Christchurch 8011, New Zealand.ORCID 0000-0003-4069-0109
Trevor AndersonMicrobiology Department, Virology/Serology Section, Canterbury Health Laboratories, Christchurch 8011, New Zealand.
Richard T ClinghanGeneral Medicine Department, Ashburton Hospital, Ashburton 7700, New Zealand.
Anja M WernoMicrobiology Department, Virology/Serology Section, Canterbury Health Laboratories, Christchurch 8011, New Zealand.
Canterbury Health Laboratories · NZChristchurch Hospital · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we describe a small enterovirus outbreak including nine cases of aseptic meningitis in a New Zealand hospital in 2017. Most patients had a lymphocytic predominance in the CSF, their length of stay was short, and there were no paediatric cases or ICU admissions. VP1 genotyping revealed that the outbreak was caused by an echovirus E30 strain closely related to strains reported from the US, UK, Brazil, and Denmark. They all form a separate cluster within lineage "h", which leads to the proposal of establishing a new lineage tentatively named "j" for this group of echovirus E30 strains. However, whole genome sequencing and reference mapping to echovirus E30 sequences showed very poor mapping of reads to the 3' half of the genome. Further bioinformatic analysis indicated that the causative agent of this outbreak might be a mosaic triple-recombinant enterovirus composed of echovirus E6, echovirus E11, and echovirus E30 genome segments.

Indexed as

Echovirus InfectionsEnterovirus InfectionsMeningitis, AsepticChildDisease OutbreaksEnterovirus B, HumanHumansMolecular EpidemiologyNew ZealandPhylogenyRNA, ViralRNA, Viralenterovirusmeningitismolecular epidemiologyrecombination

Identifiers

PMID35458388
PMCPMC9030895
OpenAlexW4220835906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.