ArticlePolymers2022
Evaluation of Antimicrobial and Anti-Biofilm Formation Activities of Novel Poly(vinyl alcohol) Hydrogels Reinforced with Crosslinked Chitosan and Silver Nano-Particles.
Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 45 citations in OpenAlex.
- Histidine-conjugated chitosan as efficient adsorbent for Congo red dye elimination from aqueous solution.RSC advances · 2026Article
- Efficient adsorption of fast green dye by chitosan modified with cyanoguanidine: statistical modelling, kinetic, and isotherm studies.BMC chemistry · 2026Article
- Adsorption of Ciprofloxacin onto CMCs/XG Hydrogel: Optimization, Kinetic, and Isotherm Studies.Polymers · 2026Article
- Synergistic inhibition of agr quorum sensing in methicillin-resistantMicrobiology spectrum · 2026Article
- Novel xanthan gum hydrogels boosted with crosslinked carboxymethyl chitosan and zinc oxide nanoparticles: synthesis, characterization and biological activity evaluation.BMC chemistry · 2025Article
- Article
- Carboxymethyl cellulose assisted reforming of poly acrylic acid co methyl methacrylate composite for wastewater treatment and effective hosting of antimicrobial silver.Scientific reports · 2025Article
- Silver nanoparticles incorporated dental restorative resin and its antibiofilm effect.Royal Society open science · 2024Article
- Poly (Vinyl Alcohol) Hydrogels Boosted with Cross-Linked Chitosan and Silver Nanoparticles for Efficient Adsorption of Congo Red and Crystal Violet Dyes.Gels (Basel, Switzerland) · 2023Article
- Wound Gel with Antimicrobial Effects Based on Polyvinyl Alcohol and Functional Aryloxycyclotriphosphazene.Polymers · 2023Article
- Silver Nanoparticles Loaded on Chitosan-g-PVA Hydrogel for the Wound-Healing Applications.Molecules (Basel, Switzerland) · 2023Article
- Article
- Article
- Advanced Hydrogels Combined with Silver and Gold Nanoparticles against Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2023Review
- Natural Strategies as Potential Weapons against Bacterial Biofilms.Life (Basel, Switzerland) · 2022Review
- Waterproof and Moisture-Permeable Polyurethane Nanofiber Membrane with High Strength, Launderability, and Durable Antimicrobial Properties.Nanomaterials (Basel, Switzerland) · 2022Article
- Antimicrobial Biomaterial on Sutures, Bandages and Face Masks with Potential for Infection Control.Polymers · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Novel hydrogels were prepared by blending chitosan and poly(vinyl alcohol), PVA, then crosslinking the resulting blends using trimellitic anhydride isothiocyanate at a concentration based on chitosan content in the blends. The weight ratios of chitosan: PVA in the blends were 1:3, 1:1, and 3:1 to produce three hydrogels symbolized as H13, H11, and H31, respectively. For a comparison, H10 was also prepared by crosslinking pure chitosan with trimellitic anhydride isothiocyanate. For further modification, three H31/silver nanocomposites (AgNPs) were synthesized using three different concentrations of silver nitrate to obtain H31/AgNPs1%, H31/AgNPs3% and H31/AgNPs5%. The structures of the prepared samples were emphasized using various analytical techniques. PVA has no inhibition activity against the tested microbes and biofilms. The antimicrobial and anti-biofilm formation activities of the investigated samples was arranged as: H31/AgNPs5% ≥ H31/AgNPs3% > H31/AgNPs1% > H10 > H31 > H11 > H13 > chitosan. H31/AgNPs5% and H31/AgNPs3% were more potent than Vancomycin and Amphotericin B against most of the tested microbes. Interestingly, H31 and H31/AgNPs3% were safe on the normal human cells. Consequently, hydrogels resulting from crosslinked blends of chitosan and PVA loaded with AgNPs in the same structure have significantly reinforced the antimicrobial and inhibition activity against the biofilms of PVA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.