Evidence map›Paper›PMID 35458202›Full record

ArticleNutrients2022

The Development of the Davis Food Glycopedia-A Glycan Encyclopedia of Food.

Juan J Castillo, Garret Couture, Nikita P Bacalzo, Ye Chen, Elizabeth L Chin, Sarah E Blecksmith, Yasmine Y Bouzid, Yael Vainberg, Chad Masarweh, Qingwen Zhou and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06395324 (Fiber Effectively Educates & Directs the Microbiome Study), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06395324 nacompletednot on this mapstarted 2024, after this paper: background citation

Fiber Effectively Educates & Directs the Microbiome Study

TypeinterventionalSponsorUniversity of California, DavisRan2024 to 2025Enrolled48ConditionsMicrobial ColonizationArmsHigh arabinose diet
3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Review
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Juan J CastilloDepartment of Chemistry, University of California Davis, Davis, CA 95616, USA.
Garret CoutureDepartment of Chemistry, University of California Davis, Davis, CA 95616, USA.ORCID 0000-0002-8947-4354
Nikita P BacalzoDepartment of Chemistry, University of California Davis, Davis, CA 95616, USA.
Ye ChenDepartment of Chemistry, University of California Davis, Davis, CA 95616, USA.ORCID 0000-0002-6379-1968
Elizabeth L ChinWestern Human Nutrition Research Center, USDA Agricultural Research Service, Davis, CA 95616, USA.
Sarah E BlecksmithDepartment of Nutrition, University of California Davis, Davis, CA 95616, USA.
Yasmine Y BouzidDepartment of Nutrition, University of California Davis, Davis, CA 95616, USA.
Yael VainbergFoods for Health Institute, University of California Davis, Davis, CA 95616, USA.
Chad MasarwehFoods for Health Institute, University of California Davis, Davis, CA 95616, USA.ORCID 0000-0003-2482-8972
Qingwen ZhouDepartment of Chemistry, University of California Davis, Davis, CA 95616, USA.ORCID 0000-0003-1152-5403
Jennifer T SmilowitzFoods for Health Institute, University of California Davis, Davis, CA 95616, USA.
J Bruce GermanFoods for Health Institute, University of California Davis, Davis, CA 95616, USA.
David A MillsFoods for Health Institute, University of California Davis, Davis, CA 95616, USA.ORCID 0000-0003-1913-9865
Danielle G LemayWestern Human Nutrition Research Center, USDA Agricultural Research Service, Davis, CA 95616, USA.ORCID 0000-0003-3318-0485
Carlito B LebrillaDepartment of Chemistry, University of California Davis, Davis, CA 95616, USA.ORCID 0000-0001-7190-5323

Funding

Annotating carbohydrate structures to develop markers for consumption of foodR01DK124193 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEBRILLA, CARLITO B, LEMAY, DANIELLE GUYANNE · 2020 to 2024
$2.9M
Agricultural Research Service 2032-51530-026-000-DAgriculture and Food Research Initiative 2020-67021-32855NIH HHS R01DK124193
6 · The paper itself

Abstract

The molecular complexity of the carbohydrates consumed by humans has been deceptively oversimplified due to a lack of analytical methods that possess the throughput, sensitivity, and resolution required to provide quantitative structural information. However, such information is becoming an integral part of understanding how specific glycan structures impact health through their interaction with the gut microbiome and host physiology. This work presents a detailed catalogue of the glycans present in complementary foods commonly consumed by toddlers during weaning and foods commonly consumed by American adults. The monosaccharide compositions of over 800 foods from diverse food groups including Fruits, Vegetables, Grain Products, Beans, Peas, Other Legumes, Nuts, Seeds; Sugars, Sweets and Beverages; Animal Products, and more were obtained and used to construct the "Davis Food Glycopedia" (DFG), an open-access database that provides quantitative structural information on the carbohydrates in food. While many foods within the same group possessed similar compositions, hierarchical clustering analysis revealed similarities between different groups as well. Such a Glycopedia can be used to formulate diets rich in specific monosaccharide residues to provide a more targeted modulation of the gut microbiome, thereby opening the door for a new class of prophylactic or therapeutic diets.

Indexed as

FabaceaeFoodAnimalsDietFruitMonosaccharidesPolysaccharidesVegetablesMonosaccharidesPolysaccharidescomplementary foodsdietdietary carbohydratesfiberfood compositionlibrarymicrobiomemonosaccharidepolysaccharidetriple quadrupole mass spectrometry

Identifiers

PMID35458202
PMCPMC9032246

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.