Evidence map›Paper›PMID 35458119›Full record

ArticleNutrients2022

Platelet Activation Favours NOX2-Mediated Muscle Damage in Elite Athletes: The Role of Cocoa-Derived Polyphenols.

Alessandra D'Amico, Elena Cavarretta, Chiara Fossati, Paolo Borrione, Fabio Pigozzi, Giacomo Frati, Sebastiano Sciarretta, Vincenzo Costa, Fabrizio De Grandis, Antonia Nigro and 10 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 1 country.

Alessandra D'AmicoDepartment of Movement, Human and Health Sciences, University of Rome "Foro Italico", 00135 Rome, Italy.ORCID 0000-0002-5571-4583
Elena CavarrettaDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.ORCID 0000-0003-0221-6000
Chiara FossatiDepartment of Movement, Human and Health Sciences, University of Rome "Foro Italico", 00135 Rome, Italy.ORCID 0000-0002-2870-7185
Paolo BorrioneDepartment of Movement, Human and Health Sciences, University of Rome "Foro Italico", 00135 Rome, Italy.
Fabio PigozziDepartment of Movement, Human and Health Sciences, University of Rome "Foro Italico", 00135 Rome, Italy.ORCID 0000-0001-5808-9405
Giacomo FratiDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.ORCID 0000-0003-2703-3761
Sebastiano SciarrettaDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.
Vincenzo CostaAS Roma Football Club, Piazzale Dino Viola 1, 00128 Rome, Italy.
Fabrizio De GrandisVilla Stuart Sport Clinic, FIFA Medical Center of Excellence, 00135 Rome, Italy.
Antonia NigroVilla Stuart Sport Clinic, FIFA Medical Center of Excellence, 00135 Rome, Italy.
Mariangela PeruzziMediterranea, Cardiocentro, 80122 Napoli, Italy.ORCID 0000-0002-9036-8495
Fabio MiraldiDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Wael SaadeDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Antonella CalogeroDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.
Paolo RosaDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.ORCID 0000-0002-8468-0677
Gioacchino GalardoPoliclinico Umberto I, Viale Regina Elena, 328, 00161 Rome, Italy.
Lorenzo LoffredoDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Pasquale PignatelliMediterranea, Cardiocentro, 80122 Napoli, Italy.ORCID 0000-0002-2265-7455
Cristina NocellaDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Roberto CarnevaleDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.ORCID 0000-0002-6216-9595
Sapienza University of Rome · ITClinica Mediterranea · ITForo Italico University of Rome · ITIstituto Neurologico Mediterraneo · ITPoliclinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanisms of exercise-induced muscle injury with etiopathogenesis and its consequences have been described; however, the impact of different intensities of exercise on the mechanisms of muscular injury development is not well understood. The aim of this study was to exploit the relationship between platelet activation, oxidative stress and muscular injuries induced by physical exercise in elite football players compared to amateur athletes. Oxidant/antioxidant status, platelet activation and markers of muscle damage were evaluated in 23 elite football players and 23 amateur athletes. Compared to amateurs, elite football players showed lower antioxidant capacity and higher oxidative stress paralleled by increased platelet activation and muscle damage markers. Simple linear regression analysis showed that sNOX2-dp and H

Indexed as

CacaoPolyphenolsAntioxidantsAthletesBiomarkersHumansHydrogen PeroxideMuscle, SkeletalOxidative StressPlatelet ActivationAntioxidantsBiomarkersHydrogen PeroxidePolyphenolsexerciseoxidative stressplatelet activationpolyphenols

Identifiers

PMID35458119
PMCPMC9030438
OpenAlexW4224286909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.