Evidence map›Paper›PMID 35458116›Full record

ArticleNutrients2022

Nutrition and Rheumatoid Arthritis Onset: A Prospective Analysis Using the UK Biobank.

Camilla Barbero Mazzucca, Lorenza Scotti, Giuseppe Cappellano, Francesco Barone-Adesi, Annalisa Chiocchetti

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Camilla Barbero MazzuccaDipartimento di Scienze Della Salute, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, Università del Piemonte Orientale, 28100 Novara, Italy.
Lorenza ScottiDipartimento di Medicina Traslazionale, Università del Piemonte Orientale, 28100 Novara, Italy.
Giuseppe CappellanoDipartimento di Scienze Della Salute, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, Università del Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0001-5193-4688
Francesco Barone-AdesiDipartimento di Medicina Traslazionale, Università del Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0003-1550-436X
Annalisa ChiocchettiDipartimento di Scienze Della Salute, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, Università del Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0002-4349-1087
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” · IT

Funding

Medical Research Council MC_PC_17228Medical Research Council MC_QA137853Ministry of Education, Universities and Research
6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects the joints. The multifactorial etiopathogenesis of RA has been heavily investigated, but is still only partially understood. Diet can represent both a risk factor and a protective factor, based on some evidence that suggests specific properties of certain foods and their ability to increase/reduce inflammation. To date, the studies done on this topic provide discordant results and are heterogeneous in terms of design and cohort size. In this work, we investigated for the first time the relationship between nutrition and the risk of RA onset using a sample size of about half a million subjects from one of the largest publicly available biobanks that is the UK biobank. Results showed that oily fish, alcohol, coffee and breakfast cereals have protective roles in RA; whereas, tea can increase the risk of RA. In conclusion, the obtained results confirm that diet plays key roles in RA, either by promoting or by preventing RA onset and development. Future research should focus on unravelling the effects of dietary habits on immune-mediated diseases to establish better preventive strategies.

Indexed as

Arthritis, RheumatoidBiological Specimen BanksAnimalsCoffeeHumansNutritional StatusUnited KingdomCoffeeautoimmunitydietary habitsrheumatoid arthritisUK biobank

Identifiers

PMID35458116
PMCPMC9025922
OpenAlexW4224239933

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.