Evidence map›Paper›PMID 35457887›Full record

ArticleMicromachines2022

Rational Design and Numerical Analysis of a Hybrid Floating cIDE Separator for Continuous Dielectrophoretic Separation of Microparticles at High Throughput.

Yalin Li, Yan Wang, Georg R Pesch, Michael Baune, Fei Du, Xiaomin Liu

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Yalin LiCollege of Chemistry and Chemical Engineering, Qingdao University, Qingdao 266071, China.
Yan WangCollege of Chemistry and Chemical Engineering, Qingdao University, Qingdao 266071, China.ORCID 0000-0001-9417-0550
Georg R PeschChemical Process Engineering, Faculty of Production Engineering, University of Bremen, Leobener Straße 6, 28359 Bremen, Germany.ORCID 0000-0003-4676-1908
Michael BauneChemical Process Engineering, Faculty of Production Engineering, University of Bremen, Leobener Straße 6, 28359 Bremen, Germany.
Fei DuInstitute of Water Chemistry, Technische Universität Dresden, 01062 Dresden, Germany.
Xiaomin LiuCollege of Chemistry and Chemical Engineering, Qingdao University, Qingdao 266071, China.
Qingdao University · CNUniversity of Bremen · DETechnische Universität Dresden · DE

Funding

China Postdoctoral Science Foundation 2019M662301European Fonds for Reginal Development AUF0006ANational Natural Science Foundation of China 21808116National Natural Science Foundation of China 22178187Natural Science Foundation of Shandong Province ZR202102180830Taishan Scholars Program of Shandong Province tsqn201909091
6 · The paper itself

Abstract

Dielectrophoresis (DEP) enables continuous and label-free separation of (bio)microparticles with high sensitivity and selectivity, whereas the low throughput issue greatly confines its clinical application. Herein, we report a novel design of the DEP separator embedded with cylindrical interdigitated electrodes that incorporate hybrid floating electrode layout for (bio)microparticle separation at favorable throughput. To better predict microparticle trajectory in the scaled-up DEP platform, a theoretical model based on coupling of electrostatic, fluid and temperature fields is established, in which the effects of Joule heating-induced electrothermal and buoyancy flows on particles are considered. Size-based fractionation of polystyrene microspheres and dielectric properties-based isolation of MDA-MB-231 from blood cells are numerically realized, respectively, by the proposed separator with sample throughputs up to 2.6 mL/min. Notably, the induced flows can promote DEP discrimination of heterogeneous cells. This work provides a reference on tailoring design of enlarged DEP platforms for highly efficient separation of (bio)samples at high throughput.

Indexed as

bio- and non-bioparticle separationdielectrophoresis (DEP)high throughputhybrid floating electrodeJoule heating

Identifiers

PMID35457887
PMCPMC9026825
OpenAlexW4224220650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.