Evidence map›Paper›PMID 35457866›Full record

ArticleMicromachines2022

Accelerated Skin Wound Healing Using Flexible Photovoltaic-Bioelectrode Electrical Stimulation.

Chao Han, Junfei Huang, Aodi Zhangji, Xufeng Tong, Kaige Yu, Kai Chen, Xinlan Liu, Yang Yang, Yuxin Chen, Waqar Ali Memon and 6 more

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. The Potential of Electrical Stimulation and Smart Textiles for Patients with Diabetes Mellitus.Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 2 countries.

Chao HanDepartment of Plastic Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510515, China.
Junfei HuangDepartment of Plastic and Aesthetic Surgery, Nanfang Hospital of Southern Medical University, Guangzhou 510515, China.
Aodi ZhangjiFrontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an 710054, China.
Xufeng TongThe Faculty of Electrical Engineering and Computer Science, Ningbo University, Ningbo 315211, China.
Kaige YuThe Faculty of Electrical Engineering and Computer Science, Ningbo University, Ningbo 315211, China.
Kai ChenThe Faculty of Electrical Engineering and Computer Science, Ningbo University, Ningbo 315211, China.
Xinlan LiuMedical College, Ningbo University, Ningbo 315000, China.
Yang YangDepartment of Plastic and Reconstructive Surgery, Zhongshan Hospital of Fudan University, Shanghai 200032, China.
Yuxin ChenThe First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China.
Waqar Ali MemonCAS Key Laboratory of Nanosystem and Hierarchical Fabrication, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, China.
Kamran AminCAS Key Laboratory of Nanosystem and Hierarchical Fabrication, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, China.
Wanlei GaoThe Faculty of Electrical Engineering and Computer Science, Ningbo University, Ningbo 315211, China.
Zexing DengCollege of Materials Science and Engineering, Xi'an University of Science and Technology, Xi'an 710054, China.
Kun ZhouSchool of Science and Engineering, The Chinese University of Hong Kong, Shenzhen 518172, China.
Yuheng WangThe Faculty of Electrical Engineering and Computer Science, Ningbo University, Ningbo 315211, China.ORCID 0000-0001-6394-1455
Xiangdong QiDepartment of Plastic Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510515, China.
Ningbo University · CNNational Center for Nanoscience and Technology · CNZhujiang Hospital · CNChinese University of Hong Kong, Shenzhen · CNFirst Affiliated Hospital Zhejiang University · CNFudan University · CNNanfang Hospital · CNXi'an Jiaotong University · CNXi'an University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Owing to the complex and long-term treatment of foot wounds due to diabetes and the limited mobility of patients, advanced clinical surgery often uses wearable flexible devices for auxiliary treatment. Therefore, there is an urgent need for self-powered biomedical devices to reduce the extra weight. We have prepared an electrically stimulated MEMS (Micro Electromechanical System) electrode integrated with wearable OPV (Organic photovoltaic). The wearable OPV is constructed of a bio-affinity PET-ITO substrate and a hundred-nanometer organic layer. Under sunlight and near-infrared light irradiation, a voltage and current are supplied to the MEMS electrode to generate an exogenous lateral electric field directed to the center of the wound. The results of in vitro cell experiments and diabetic skin-relieving biological experiments showed the proliferation of skin fibroblasts and the expression of transforming growth factors increased, and the skin wounds of diabetic mouse healed faster. Our research provides new insights for the clinical treatment of diabetes.

Indexed as

electrical stimulationflexible photovoltaic-bioelectrodeMEMSwound healing

Identifiers

PMID35457866
PMCPMC9032666
OpenAlexW4220767903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.