Evidence map›Paper›PMID 35457536›Full record

ReviewInternational journal of environmental research and public health2022

Availability, Toxicology and Medical Significance of Antimony.

Argyrios Periferakis, Ana Caruntu, Aristodemos-Theodoros Periferakis, Andreea-Elena Scheau, Ioana Anca Badarau, Constantin Caruntu, Cristian Scheau

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 72 citations in OpenAlex.

  1. Article
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  16. Gut Microbiota and Its Metabolite Taurine-International journal of molecular sciences · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Capsaicin: Emerging Pharmacological and Therapeutic Insights.Current issues in molecular biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Argyrios PeriferakisDepartment of Physiology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-8319-7464
Ana CaruntuDepartment of Oral and Maxillofacial Surgery, The "Carol Davila" Central Military Emergency Hospital, 010825 Bucharest, Romania.ORCID 0000-0003-4200-3069
Aristodemos-Theodoros PeriferakisDepartment of Physiology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Andreea-Elena ScheauDepartment of Radiology and Medical Imaging, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Ioana Anca BadarauDepartment of Physiology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Constantin CaruntuDepartment of Physiology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0003-4530-7965
Cristian ScheauDepartment of Physiology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0001-7676-6393
Carol Davila University of Medicine and Pharmacy · ROInstitutul Clinic Fundeni · ROTitu Maiorescu University · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimony has been known and used since ancient times, but its applications have increased significantly during the last two centuries. Aside from its few medical applications, it also has industrial applications, acting as a flame retardant and a catalyst. Geologically, native antimony is rare, and it is mostly found in sulfide ores. The main ore minerals of antimony are antimonite and jamesonite. The extensive mining and use of antimony have led to its introduction into the biosphere, where it can be hazardous, depending on its bioavailability and absorption. Detailed studies exist both from active and abandoned mining sites, and from urban settings, which document the environmental impact of antimony pollution and its impact on human physiology. Despite its evident and pronounced toxicity, it has also been used in some drugs, initially tartar emetics and subsequently antimonials. The latter are used to treat tropical diseases and their therapeutic potential for leishmaniasis means that they will not be soon phased out, despite the fact the antimonial resistance is beginning to be documented. The mechanisms by which antimony is introduced into human cells and subsequently excreted are still the subject of research; their elucidation will enable us to better understand antimony toxicity and, hopefully, to improve the nature and delivery method of antimonial drugs.

Indexed as

AntimonyLeishmaniasisHumansMineralsMiningAntimonyMineralsantimonyexposurehealth impactpathophysiologyresistancestibnitetoxicity

Identifiers

PMID35457536
PMCPMC9030621
OpenAlexW4223510086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.