Evidence map›Paper›PMID 35457272›Full record

ReviewInternational journal of molecular sciences2022

Revisiting the Role of Astrocytic MAOB in Parkinson's Disease.

Min-Ho Nam, Moonsun Sa, Yeon Ha Ju, Mingu Gordon Park, C Justin Lee

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 57 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Min-Ho NamBrain Science Institute, Korea Institute of Science and Technology, Seoul 02792, Korea.ORCID 0000-0002-6191-1268
Moonsun SaKU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul 02841, Korea.ORCID 0000-0002-5066-7706
Yeon Ha JuBrain Science Institute, Korea Institute of Science and Technology, Seoul 02792, Korea.ORCID 0000-0001-8307-8062
Mingu Gordon ParkKU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul 02841, Korea.
C Justin LeeKU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul 02841, Korea.
Korea University · KRKorea Institute of Brain Science · KRKyung Hee University · KR

Funding

Institute for Basic Science IBS-R001-D2National Research Foundation of Korea 2018M3C7A1056897
6 · The paper itself

Abstract

Monoamine oxidase-B (MAOB) has been believed to mediate the degradation of monoamine neurotransmitters such as dopamine. However, this traditional belief has been challenged by demonstrating that it is not MAOB but MAOA which mediates dopamine degradation. Instead, MAOB mediates the aberrant synthesis of GABA and hydrogen peroxide (H

Indexed as

AstrocytesMonoamine OxidaseParkinson DiseaseDopaminegamma-Aminobutyric AcidHumansHydrogen PeroxideDopaminegamma-Aminobutyric AcidHydrogen PeroxideMonoamine OxidaseastrocytedopamineGABAH2O2MAOBParkinson’s disease

Identifiers

PMID35457272
PMCPMC9028367
OpenAlexW4224218636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.