Evidence map›Paper›PMID 35457253›Full record

ReviewInternational journal of molecular sciences2022

Therapeutic Approaches of Ryanodine Receptor-Associated Heart Diseases.

Norbert Szentandrássy, Zsuzsanna É Magyar, Judit Hevesi, Tamás Bányász, Péter P Nánási, János Almássy

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Heart on Fire: UnmaskingMethodist DeBakey cardiovascular journal · 2025
    Article
  4. Article
  5. Article
  6. Calmodulin Mutations in Human Disease.Channels (Austin, Tex.) · 2023
    Review
  7. RYR2-ryanodinopathies: from calcium overload to calcium deficiency.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  8. [Enhanced endoplasmic reticulum RyR1 receptor phosphorylation leads to diaphragmatic dysfunction in septic rats].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023
    Article
  9. Article
  10. Holiday Heart Syndrome, Atrial Fibrillation, and RyR2 Antagonist.Journal of cardiovascular pharmacology · 2022
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Norbert SzentandrássyDepartment of Physiology, Faculty of Medicine, University of Debrecen, 98 Nagyerdei krt, 4032 Debrecen, Hungary.
Zsuzsanna É MagyarDepartment of Physiology, Faculty of Medicine, University of Debrecen, 98 Nagyerdei krt, 4032 Debrecen, Hungary.
Judit HevesiDepartment of Orthodontics, Faculty of Dentistry, University of Debrecen, 98 Nagyerdei krt, 4032 Debrecen, Hungary.
Tamás BányászDepartment of Physiology, Faculty of Medicine, University of Debrecen, 98 Nagyerdei krt, 4032 Debrecen, Hungary.ORCID 0000-0003-3894-0738
Péter P NánásiDepartment of Physiology, Faculty of Medicine, University of Debrecen, 98 Nagyerdei krt, 4032 Debrecen, Hungary.
János AlmássyDepartment of Physiology, Faculty of Medicine, University of Debrecen, 98 Nagyerdei krt, 4032 Debrecen, Hungary.
University of Debrecen · HUSemmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac diseases are the leading causes of death, with a growing number of cases worldwide, posing a challenge for both healthcare and research. Therefore, the most relevant aim of cardiac research is to unravel the molecular pathomechanisms and identify new therapeutic targets. Cardiac ryanodine receptor (RyR2), the Ca

Indexed as

Ryanodine Receptor Calcium Release ChannelTachycardia, VentricularArrhythmogenic Right Ventricular DysplasiaCalciumCalcium SignalingHumansMutationSarcoplasmic ReticulumCalciumRyanodine Receptor Calcium Release Channelcarvedilolcatecholaminergic polymorphic ventricular tachycardiacongestive heart failureCPVTdantroleneflecainideryanodine receptorryanopathiesRyR

Identifiers

PMID35457253
PMCPMC9031589
OpenAlexW4224265991

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.