Evidence map›Paper›PMID 35457206›Full record

ReviewInternational journal of molecular sciences2022

Nutrient Sensing and Biofilm Modulation: The Example of L-arginine in

Chiara Scribani Rossi, Laura Barrientos-Moreno, Alessio Paone, Francesca Cutruzzolà, Alessandro Paiardini, Manuel Espinosa-Urgel, Serena Rinaldo

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Altered distribution of chronicity-deficientMicrobiology (Reading, England) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Arginine at the host-pathogen interface.Infection and immunity · 2025
    Review
  13. Article
  14. Arginine utilization inInfection and immunity · 2025
    Article
  15. Article
  16. Article
  17. The adaptability ofFrontiers in cellular and infection microbiology · 2025
    Review
  18. Exploring the Metabolic Response of Pseudomonas putida to L-arginine.Advances in experimental medicine and biology · 2025
    Article
  19. The effect of cCMP and cUMP on growth ofFrontiers in microbiology · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Chiara Scribani RossiLaboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci Bolognetti-Department of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, 00185 Rome, Italy.
Laura Barrientos-MorenoNational Biofilms Innovation Centre, Biodiscovery Institute-School of Life Sciences, University of Nottingham, Nottingham NG7 2RD, UK.
Alessio PaoneLaboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci Bolognetti-Department of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0001-9406-3982
Francesca CutruzzolàLaboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci Bolognetti-Department of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, 00185 Rome, Italy.
Alessandro PaiardiniLaboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci Bolognetti-Department of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0001-9078-7545
Manuel Espinosa-UrgelDepartment of Biotechnology and Environmental Protection, Estación Experimental del Zaidin, CSIC, 18008 Granada, Spain.ORCID 0000-0002-6862-0682
Serena RinaldoLaboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci Bolognetti-Department of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-0682-023X
Istituto Pasteur · ITEstación Experimental del Zaidín · ESUniversity of Nottingham · GB

Funding

European Union ERDF A way of making EuropeIstituto Pasteur Italia - Fondazione Cenci Bolognetti Sensing arginine through the Venus Fly Trap domain to control c-di-GMP levels in Pseudomonas aeruginosa: molecular mechanism and metabolic effects of signal transduction.MCIN/AEI/10.13039/501100011033 PID2019-109372GB-I00Sapienza University of Rome RM120172A7AD98EB to SR and AR12117A63EE6037 to CSR
6 · The paper itself

Abstract

Bacterial biofilm represents a multicellular community embedded within an extracellular matrix attached to a surface. This lifestyle confers to bacterial cells protection against hostile environments, such as antibiotic treatment and host immune response in case of infections. The

Indexed as

Cyclic GMPPseudomonas aeruginosaArginineBacterial ProteinsBiofilmsCarbonNitrogenNutrientsPseudomonasArginineBacterial ProteinsCarbonCyclic GMPNitrogenNutrientsarginineArgRbiofilmc-di-GMPmetabolismnutrientsPseudomonasRmcA

Identifiers

PMID35457206
PMCPMC9028604
OpenAlexW4224039298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.