Evidence map›Paper›PMID 35457199›Full record

ArticleInternational journal of molecular sciences2022

Nrf2-Activating Bioactive Peptides Exert Anti-Inflammatory Activity through Inhibition of the NF-κB Pathway.

Federica Tonolo, Alessandra Folda, Valeria Scalcon, Oriano Marin, Alberto Bindoli, Maria Pia Rigobello

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

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  15. Jingzhi Niuhuangjiedu Tablet Ameliorates Oral MucositisCombinatorial chemistry & high throughput screening · 2025
    Article
  16. Frontiers in pharmacology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Federica TonoloDepartment of Biomedical Sciences, University of Padova, Via Ugo Bassi 58/b, 35131 Padova, Italy.ORCID 0000-0002-7780-8994
Alessandra FoldaDepartment of Biomedical Sciences, University of Padova, Via Ugo Bassi 58/b, 35131 Padova, Italy.
Valeria ScalconDepartment of Biomedical Sciences, University of Padova, Via Ugo Bassi 58/b, 35131 Padova, Italy.ORCID 0000-0002-7061-6471
Oriano MarinDepartment of Biomedical Sciences, University of Padova, Via Ugo Bassi 58/b, 35131 Padova, Italy.
Alberto BindoliInstitute of Neuroscience, CNR, Via G Colombo 3, 35131 Padova, Italy.
Maria Pia RigobelloDepartment of Biomedical Sciences, University of Padova, Via Ugo Bassi 58/b, 35131 Padova, Italy.ORCID 0000-0003-2586-3251
University of Padua · ITNeuroscience Institute · IT

Funding

Regione del Veneto FSE project cod. 2105-0007-1463-2019Regione del Veneto POR Veneto FESR 2014-2020 Asse 1 Azione 1.1.4 Progetto 3S_4H "Cibo intelligente per un futuro sostenibile"University of Padua Dept. Biomedical Sciences, BIRD 200459/20
6 · The paper itself

Abstract

Redox status and inflammation are related to the pathogenesis of the majority of diseases. Therefore, understanding the role of specific food-derived molecules in the regulation of their specific pathways is a relevant issue. Our previous studies indicated that

Indexed as

NF-E2-Related Factor 2NF-kappa BAnti-Inflammatory AgentsCaco-2 CellsHeme Oxygenase-1HumansInflammationKelch-Like ECH-Associated Protein 1LipopolysaccharidesSignal TransductionTumor Necrosis Factor-alphaAnti-Inflammatory AgentsHeme Oxygenase-1Kelch-Like ECH-Associated Protein 1LipopolysaccharidesNF-E2-Related Factor 2NF-kappa BTumor Necrosis Factor-alphaanti-inflammatoryantioxidantbioactive peptidesNF-κBNrf2

Identifiers

PMID35457199
PMCPMC9032749
OpenAlexW4224071637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.