Evidence map›Paper›PMID 35456968›Full record

ArticleInternational journal of molecular sciences2022

Replicative Stress Coincides with Impaired Nuclear DNA Damage Response in COX4-1 Deficiency.

Liza Douiev, Chaya Miller, Guy Keller, Hadar Benyamini, Bassam Abu-Libdeh, Ann Saada

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Nuclear Control of Mitochondrial Homeostasis and Venetoclax Efficacy in AML via COX4I1.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  5. Mitochondrial Factors in the Cell Nucleus.International journal of molecular sciences · 2023
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Liza DouievDepartment of Genetics, Hadassah Medical Center, Jerusalem 9112001, Israel.
Chaya MillerDepartment of Genetics, Hadassah Medical Center, Jerusalem 9112001, Israel.
Guy KellerDepartment of Genetics, Hadassah Medical Center, Jerusalem 9112001, Israel.
Hadar BenyaminiInfo-CORE, Bioinformatics Unit of the I-CORE, Hebrew University of Jerusalem, Jerusalem 9112001, Israel.
Bassam Abu-LibdehDepartment of Pediatrics and Genetics, Makassed Hospital and Al-Quds University, East Jerusalem, Palestinian Territories 91220, Israel.
Ann SaadaDepartment of Genetics, Hadassah Medical Center, Jerusalem 9112001, Israel.ORCID 0000-0003-2951-0656
Hadassah Medical Center · ILHebrew University of Jerusalem · ILAl-Makassed Islamic Charitable Society Hospital · IL

Funding

Israel Science Foundation 1059/19
6 · The paper itself

Abstract

Cytochrome

Indexed as

Cytochrome-c Oxidase DeficiencyMitochondrial DiseasesCell NucleusDNA DamageElectron Transport Complex IVHumansCOX4I1 protein, humanElectron Transport Complex IVCOX4i1cytochrome c oxidaseDNA damagemitochondriamitochondrial respiratory chainreplicative stress

Identifiers

PMID35456968
PMCPMC9029573
OpenAlexW4224277772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.