Evidence map›Paper›PMID 35456674›Full record

ArticlePharmaceutics2022

Achieving Effective Multimodal Imaging with Rare-Earth Ion-Doped CaF

Zhenfeng Yu, Yuanyuan He, Timo Schomann, Kefan Wu, Yang Hao, Ernst Suidgeest, Hong Zhang, Christina Eich, Luis J Cruz

Erratum issuedAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Rare-Earth-Metal (NdPharmaceutics · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Zhenfeng YuTranslational Nanobiomaterials and Imaging Group, Department of Radiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Yuanyuan HeTranslational Nanobiomaterials and Imaging Group, Department of Radiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0003-0156-5671
Timo SchomannTranslational Nanobiomaterials and Imaging Group, Department of Radiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0002-0948-6209
Kefan WuVan't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands.
Yang HaoTranslational Nanobiomaterials and Imaging Group, Department of Radiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0003-2708-530X
Ernst SuidgeestC.J. Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Hong ZhangVan't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands.
Christina EichTranslational Nanobiomaterials and Imaging Group, Department of Radiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0001-7839-0932
Luis J CruzTranslational Nanobiomaterials and Imaging Group, Department of Radiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.

Funding

Christina Eich SIMICA (852985);the Dutch PPS allowance made available by Health~Holland, Top Sector Life Sciences & Health for the project NANOCAST 2Luis J. Cruz CANCER (777682), PRISAR2 (872860), ACORN (807281), SIMICA (852985), BIOSAFETY (952520), PAVE (861190), CAST (857894), NOVA-MRI (859908), PIANO (956477).Timo Schomann CANCER (777682);SIMICA (852985)Yuanyuan He CANCER (777682); PRISAR2 (872860).Zhenfeng Yu the China Scholarship Council
6 · The paper itself

Abstract

Nowadays, cancer poses a significant hazard to humans. Limitations in early diagnosis techniques not only result in a waste of healthcare resources but can even lead to delays in diagnosis and treatment, consequently reducing cure rates. Therefore, it is crucial to develop an imaging probe that can provide diagnostic information precisely and rapidly. Here, we used a simple hydrothermal method to design a multimodal imaging probe based on the excellent properties of rare-earth ions. Calcium fluoride co-doped with ytterbium, gadolinium, and neodymium (CaF

Indexed as

magnetic resonancemultimodal imagingNIR-II fluorescencephotoacousticrare-earth ions

Identifiers

PMID35456674
PMCPMC9024546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.