Evidence map›Paper›PMID 35456620›Full record

ArticlePharmaceutics2022

Mechanisms Underlying Synergistic Killing of Polymyxin B in Combination with Cannabidiol against

Maytham Hussein, Rafah Allobawi, Irini Levou, Mark A T Blaskovich, Gauri G Rao, Jian Li, Tony Velkov

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. International journal of molecular sciences · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Cannabidiol (CBD) Acts as an Antioxidant onAntibiotics (Basel, Switzerland) · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Fingolimod synergizes and reversesFrontiers in microbiology · 2024
    Article
  15. Article
  16. Review
  17. Article
  18. CBD resistantFrontiers in medicine · 2023
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Maytham HusseinDepartment of Biochemistry and Pharmacology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0001-5922-7312
Rafah AllobawiDepartment of Biochemistry and Pharmacology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Irini LevouDepartment of Biochemistry and Pharmacology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Mark A T BlaskovichInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0001-9447-2292
Gauri G RaoDivision of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, USA.
Jian LiMonash Biomedicine Discovery Institute, Department of Microbiology, Monash University, Clayton, VIC 3800, Australia.
Tony VelkovDepartment of Biochemistry and Pharmacology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0002-0017-7952
The University of Melbourne · AUAustralian Regenerative Medicine Institute · AUThe University of Queensland · AUUniversity of North Carolina at Chapel Hill · US

Funding

Pharmacology of intrathecal/intraventricular polymyxins: A systems-based approachR01AI146241 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RAO, GAURI G, VELKOV, TONY · 2019 to 2023
$3.0M
NIAID NIH HHS R01 AI146241The National Institute of Allergy and Infectious Diseases of the National Institutes of Health R01 AI132681 and AI146160
6 · The paper itself

Abstract

Polymyxins have resurged as the last-resort antibiotics against multidrug-resistant

Indexed as

antimicrobial peptidesantimicrobial resistancecannabidiolMDR Gram-negativemetabolomics

Identifiers

PMID35456620
PMCPMC9025570
OpenAlexW4224315183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.