Evidence map›Paper›PMID 35456475›Full record

ArticleGenes2022

An Alternatively Spliced Variant of METTL3 Mediates Tumor Suppression in Hepatocellular Carcinoma.

Rui-Yao Xu, Zhan Ding, Qing Zhao, Tiao-Ying Ke, Shu Chen, Xing-Yu Wang, Yao-Yun Wang, Meng-Fei Sheng, Wei Wang, Ni Long and 3 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Epigenetic control of skeletal muscle atrophy.Cellular & molecular biology letters · 2024
    Review
  6. RNA m6A methylation regulators in liver cancer.Cancer cell international · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Rui-Yao XuSchool of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China.
Zhan DingState Key Laboratory of Virology, Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan 430072, China.
Qing ZhaoSchool of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China.
Tiao-Ying KeSchool of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China.
Shu ChenSchool of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China.
Xing-Yu WangSchool of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China.
Yao-Yun WangSchool of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China.
Meng-Fei ShengSchool of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China.
Wei WangDepartment of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei 230032, China.
Ni LongState Key Laboratory of Virology, Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan 430072, China.
Yu-Xian ShenSchool of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China.
Yong-Zhen XuState Key Laboratory of Virology, Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan 430072, China.
Wei ShaoSchool of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China.ORCID 0000-0003-1763-9911
Anhui Medical University · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many post-transcriptional mRNA processing steps play crucial roles in tumorigenesis and the progression of cancers, such as N6-methyladenosine (m

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAdenosineHumansMethyltransferasesRNA, MessengerAdenosineMethyltransferasesMETTL3 protein, humanRNA, Messengerhepatocellular carcinomaMETTL3RNA m6Asplice variantstumor suppressor

Identifiers

PMID35456475
PMCPMC9031889
OpenAlexW4223602851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.