Evidence map›Paper›PMID 35456450›Full record

ArticleGenes2022

Identification and Somatic Characterization of the Germline

Vittoria Disciglio, Paola Sanese, Candida Fasano, Claudio Lotesoriere, Anna Maria Valentini, Giovanna Forte, Martina Lepore Signorile, Katia De Marco, Valentina Grossi, Ivan Lolli and 2 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Identification of a novel germlineGenes & diseases · 2024
    Article
  3. Clinical and Molecular Characterization ofInternational journal of molecular sciences · 2024
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Vittoria DisciglioMedical Genetics, National Institute of Gastroenterology—IRCCS "S. de Bellis" Research Hospital, Castellana Grotte, 70013 Bari, Italy.
Paola SaneseMedical Genetics, National Institute of Gastroenterology—IRCCS "S. de Bellis" Research Hospital, Castellana Grotte, 70013 Bari, Italy.
Candida FasanoMedical Genetics, National Institute of Gastroenterology—IRCCS "S. de Bellis" Research Hospital, Castellana Grotte, 70013 Bari, Italy.ORCID 0000-0001-5878-3480
Claudio LotesoriereOncology Unit, National Institute of Gastroenterology—IRCCS "S. de Bellis" Research Hospital, Castellana Grotte, 70013 Bari, Italy.ORCID 0000-0002-7999-9739
Anna Maria ValentiniDepartment of Pathology, National Institute of Gastroenterology—IRCCS "S. de Bellis" Research Hospital, Castellana Grotte, 70013 Bari, Italy.ORCID 0000-0002-6798-808X
Giovanna ForteMedical Genetics, National Institute of Gastroenterology—IRCCS "S. de Bellis" Research Hospital, Castellana Grotte, 70013 Bari, Italy.
Martina Lepore SignorileMedical Genetics, National Institute of Gastroenterology—IRCCS "S. de Bellis" Research Hospital, Castellana Grotte, 70013 Bari, Italy.
Katia De MarcoMedical Genetics, National Institute of Gastroenterology—IRCCS "S. de Bellis" Research Hospital, Castellana Grotte, 70013 Bari, Italy.
Valentina GrossiMedical Genetics, National Institute of Gastroenterology—IRCCS "S. de Bellis" Research Hospital, Castellana Grotte, 70013 Bari, Italy.
Ivan LolliOncology Unit, National Institute of Gastroenterology—IRCCS "S. de Bellis" Research Hospital, Castellana Grotte, 70013 Bari, Italy.
Filomena CariolaMedical Genetics, National Institute of Gastroenterology—IRCCS "S. de Bellis" Research Hospital, Castellana Grotte, 70013 Bari, Italy.
Cristiano SimoneMedical Genetics, National Institute of Gastroenterology—IRCCS "S. de Bellis" Research Hospital, Castellana Grotte, 70013 Bari, Italy.
Gastroenterology Hospital "Saverio de Bellis" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic variants located in non-coding regions can affect processes that regulate protein expression, functionally contributing to human disease. Germline heterozygous mutations in the non-coding region of the

Indexed as

AdenocarcinomaBreast NeoplasmsHamartoma Syndrome, MultipleEsophageal NeoplasmsFemaleGerm CellsHumansPTEN PhosphohydrolasePTEN PhosphohydrolasePTEN protein, humanbreast cancergastroesophageal junction adenocarcinomaPTEN hamartoma tumor syndrome (PHTS)PTEN promoter

Identifiers

PMID35456450
PMCPMC9025445
OpenAlexW4224312610

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.