Evidence map›Paper›PMID 35456442›Full record

ArticleGenes2022

Rare and Common Variants Uncover the Role of the Atria in Coarctation of the Aorta.

Wenjuan Zhu, Kylia Williams, Cullen Young, Jiaunn-Huey Lin, Polakit Teekakirikul, Cecilia W Lo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Wenjuan ZhuCentre for Cardiovascular Genomics and Medicine, Chinese University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0003-2724-4825
Kylia WilliamsDepartment of Developmental Biology, University of Pittsburgh School of Medicine, 530 45th St, Pittsburgh, PA 15201, USA.ORCID 0000-0003-1163-4546
Cullen YoungDepartment of Developmental Biology, University of Pittsburgh School of Medicine, 530 45th St, Pittsburgh, PA 15201, USA.
Jiaunn-Huey LinDepartment of Critical Care Medicine, University of Pittsburgh School of Medicine, 530 45th St, Pittsburgh, PA 15201, USA.
Polakit TeekakirikulCentre for Cardiovascular Genomics and Medicine, Chinese University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0003-2407-7355
Cecilia W LoDepartment of Developmental Biology, University of Pittsburgh School of Medicine, 530 45th St, Pittsburgh, PA 15201, USA.
University of Pittsburgh · USChinese University of Hong Kong · HK

Funding

Modeling the complex genetics of congenital heart disease in miceR01HL132024 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LO, CECILIA W. · 2016 to 2019
$3.4M
6 · The paper itself

Abstract

Coarctation of the aorta (CoA) and bicuspid aortic valve (BAV) often cooccur and are genetically linked congenital heart defects (CHD). While CoA is thought to have a hemodynamic origin from ventricular dysfunction, we provide evidence pointing to atrial hemodynamics based on investigating the genetic etiology of CoA. Previous studies have shown a rare

Indexed as

Aortic CoarctationBicuspid Aortic Valve DiseaseHeart Defects, CongenitalHeart Valve DiseasesAnimalsAortic ValveCoenzyme AHumansMiceCoenzyme Aatrial dominancecoarctation of the aortaMYH6PCHDA

Identifiers

PMID35456442
PMCPMC9032275
OpenAlexW4224309803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.