Evidence map›Paper›PMID 35456397›Full record

ArticleGenes2022

Identification of a Cancer-Predisposing Germline

Audrey N Jajosky, Anna L Mitchell, Mahmut Akgul, Shashirekha Shetty, Jennifer M Yoest, Stanton L Gerson, Navid Sadri, Kwadwo A Oduro

Open access · goldAbstract readCase Reports
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Guideline
  2. GermlineGenes · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Audrey N JajoskyDepartment of Pathology and Laboratory Medicine, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106, USA.ORCID 0000-0002-8265-2496
Anna L MitchellDepartment of Genetics and Genome Sciences, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106, USA.
Mahmut AkgulDepartment of Pathology and Laboratory Medicine, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106, USA.
Shashirekha ShettyDepartment of Pathology and Laboratory Medicine, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106, USA.
Jennifer M YoestDepartment of Pathology and Laboratory Medicine, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106, USA.ORCID 0000-0003-3118-4052
Stanton L GersonDepartment of Medicine, Hematology Oncology Division, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106, USA.ORCID 0000-0003-3106-2549
Navid SadriDepartment of Pathology and Laboratory Medicine, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106, USA.ORCID 0000-0001-5051-717X
Kwadwo A OduroDepartment of Pathology and Laboratory Medicine, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106, USA.
University Hospitals of Cleveland · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Germline disruptive variants in

Indexed as

GliomaLeukemia, Lymphocytic, Chronic, B-CellLymphoma, Non-HodgkinMelanomaAgedHumansMaleShelterin ComplexTelomereTelomere-Binding ProteinsPOT1 protein, humanShelterin ComplexTelomere-Binding Proteinscancer geneticsgermline POT1 alterationhereditary cancer predispositionsplenic marginal zone lymphoma

Identifiers

PMID35456397
PMCPMC9028718
OpenAlexW4221069782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.