Evidence map›Paper›PMID 35456382›Full record

ArticleGenes2022

miR-152-3p Represses the Proliferation of the Thymic Epithelial Cells by Targeting

Ying Li, Xintong Wang, Qingru Wu, Fenfen Liu, Lin Yang, Bishuang Gong, Kaizhao Zhang, Yongjiang Ma, Yugu Li

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ying LiCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Xintong WangCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Qingru WuCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Fenfen LiuCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Lin YangCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Bishuang GongCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Kaizhao ZhangCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Yongjiang MaCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Yugu LiCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0001-5376-7289
South China Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) control the proliferation of thymic epithelial cells (TECs) for thymic involution. Previous studies have shown that expression levels of miR-152-3p were significantly increased in the thymus and TECs during the involution of the mouse thymus. However, the possible function and potential molecular mechanism of miR-152-3p remains unclear. This study identified that the overexpression of miR-152-3p can inhibit, while the inhibition of miR-152-3p can promote, the proliferation of murine medullary thymic epithelial cell line 1 (MTEC1) cells. Moreover, miR-152-3p expression was quantitatively analyzed to negatively regulate

Indexed as

MicroRNAsAnimalsCell CycleCell ProliferationEpithelial CellsMiceSmad2 ProteinMicroRNAsSmad2 ProteinSmad2 protein, mousecell proliferationmiR-152-3pSmad2thymic epithelial cells

Identifiers

PMID35456382
PMCPMC9028272
OpenAlexW4220983405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.