Evidence map›Paper›PMID 35456331›Full record

ArticleJournal of clinical medicine2022

Positivity Trends of Bacterial Cultures from Cases of Acute and Chronic Periprosthetic Joint Infections.

Rares Mircea Birlutiu, Cristian Ioan Stoica, Octav Russu, Razvan Silviu Cismasiu, Victoria Birlutiu

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rares Mircea BirlutiuFoisor Clinical Hospital of Orthopedics, Traumatology, and Osteoarticular TB, B-dul Ferdinand 35-37, Sector 2, 021382 Bucharest, Romania.ORCID 0000-0001-7400-2904
Cristian Ioan StoicaFoisor Clinical Hospital of Orthopedics, Traumatology, and Osteoarticular TB, Carol Davila University of Medicine and Pharmacy, B-dul Ferdinand 35-37, Sector 2, 021382 Bucharest, Romania.
Octav RussuDepartment of Orthopaedics and Traumatology, Clinical County Hospital, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Str. Gheorghe Marinescu 38, 311694 Targu Mures, Romania.
Razvan Silviu CismasiuFoisor Clinical Hospital of Orthopedics, Traumatology, and Osteoarticular TB, Carol Davila University of Medicine and Pharmacy, B-dul Ferdinand 35-37, Sector 2, 021382 Bucharest, Romania.
Victoria BirlutiuFaculty of Medicine, Lucian Blaga University of Sibiu, Str. Lucian Blaga, Nr. 2A, 550169 Sibiu, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is no clear distinction in the literature regarding the positivity trends of bacterial cultures in acute and chronic prosthetic joint infections.

methodsWe prospectively included in this study all consecutive patients, aged over 18 years, that were hospitalized from September 2016 through December 2019, that underwent a joint arthroplasty revision surgery.

resultsForty patients were included in our analysis, 11 acute/acute hematogenous and 29 chronic PJIs. We were able to identify all strains of acute/acute hematogenous PJIs within 3 days, whereas this took 8 days for chronic PJIs. Sonication fluid cultures increased the positivity rate and helped in identifying rare pathogens such as

conclusionThere was a different positivity trend in bacterial cultures. Empiric broad-spectrum antibiotic therapy can be re-evaluated after 3 days for acute PJIs. A prolonged incubation time, especially in the case of chronic PJIs, is mandatory; however, extending the incubation period beyond 14 days would not further improve the ability to identify microorganisms.

Indexed as

acutebacterial cultureschronicdiagnosisperiprosthetic joint infectionPJIpositivity trends

Identifiers

PMID35456331
PMCPMC9030751

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.