Evidence map›Paper›PMID 35456305›Full record

ArticleJournal of clinical medicine2022

Noninvasive Evaluation of Intraventricular Flow Dynamics by the HyperDoppler Technique: First Application to Normal Subjects, Athletes, and Patients with Heart Failure.

Andrea Fiorencis, Marco Pepe, Vittorio Smarrazzo, Marika Martini, Salvatore Severino, Valeria Pergola, Marco Evangelista, Pierluigi Incarnato, Marco Previtero, Marco Maglione and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Intracardiac flow dynamics in mitral regurgitation: state of the art.European heart journal. Imaging methods and practice · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Effect of Aging on Intraventricular Kinetic Energy and Energy Dissipation.Journal of cardiovascular development and disease · 2023
    Review
  10. Article
  11. Article
  12. From Strain toward Hyperdoppler Echocardiographic Evaluation in Sports Medicine.International journal of environmental research and public health · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Andrea FiorencisDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35128 Padova, Italy.ORCID 0000-0002-5117-8445
Marco PepeDepartment of Cardiology and Cardiac Surgery, S. Michele Hospital, 81024 Maddaloni, Caserta, Italy.
Vittorio SmarrazzoCardiology Unit, Umberto I Hospital, 48022 Lugo, Ravenna, Italy.
Marika MartiniDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35128 Padova, Italy.
Salvatore SeverinoDepartment of Cardiology and Cardiac Surgery, S. Michele Hospital, 81024 Maddaloni, Caserta, Italy.
Valeria PergolaDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35128 Padova, Italy.ORCID 0000-0002-3317-7342
Marco EvangelistaDepartment of Cardiology and Cardiac Surgery, S. Michele Hospital, 81024 Maddaloni, Caserta, Italy.
Pierluigi IncarnatoDepartment of Cardiology and Cardiac Surgery, S. Michele Hospital, 81024 Maddaloni, Caserta, Italy.
Marco PreviteroDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35128 Padova, Italy.
Marco MaglioneGLM Esaote Spa, 16152 Genova, Italy.
Sabino IlicetoDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35128 Padova, Italy.
Gianni PedrizzettiDepartment of Engineering and Architecture, University of Trieste, 34127 Trieste, Italy.
Donato MeleDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35128 Padova, Italy.ORCID 0000-0002-2823-4090
University of Padua · ITCasa di Cura San Michele · ITEsaote (Italy) · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: HyperDoppler is a new echocardiographic color Doppler-based technique that can assess intracardiac flow dynamics. The aim of this study was to verify the feasibility and reproducibility of this technique in unselected patients and its capability to differentiate measures of vortex flow within the left ventricle (LV) in normal sedentary subjects, athletes, and patients with heart failure. Methods: Two hundred unselected, consecutive patients presenting at the echocardiographic laboratory, 50 normal subjects, 30 athletes, and 50 patients with chronic heart failure and LV ejection fraction <50% were enrolled. Images were acquired using a MyLab X8 echo-scanner. Area, intensity, depth, length, and kinetic energy dissipation (KED) of vortex flow were measured. Results: The HyperDoppler technique feasibility was 94.5%. According to the intraclass correlation coefficient evaluations, repeatability and reproducibility of vortex flow measures were good for vortex area (0.82, 0.85), length (0.83, 0.82), and depth (0.87, 0.84) and excellent for intensity (0.92, 0.90) and KED (0.98, 0.98). Combining different vortex flow measures, the LV flow profile of healthy sedentary individuals, athletes, and heart failure patients could be differentiated. Conclusions: HyperDoppler is a feasible, reliable, and practical technique for the assessment of LV flow dynamics and may distinguish normal subjects and patients with heart failure.

Indexed as

athletesHyperDopplerintracardiac flow dynamicskinetic energy dissipationvortex flow

Identifiers

PMID35456305
PMCPMC9026209
OpenAlexW4224081649

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.