Evidence map›Paper›PMID 35456303›Full record

ArticleJournal of clinical medicine2022

Balloon Pulmonary Angioplasty in Patients with Chronic Thromboembolic Pulmonary Hypertension in Greece: Data from the Hellenic Pulmonary Hypertension Registry.

Panagiotis Karyofyllis, Eftychia Demerouti, George Giannakoulas, Anastasia Anthi, Alexandra Arvanitaki, George Athanassopoulos, Christos Feloukidis, Ioannis Iakovou, Theodora Kostelidou, Ioanna Mitrouska and 9 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 1 country.

Panagiotis KaryofyllisCardiology Department, Onassis Cardiac Surgery Center, 17674 Athens, Greece.
Eftychia DemeroutiCardiology Department, Onassis Cardiac Surgery Center, 17674 Athens, Greece.ORCID 0000-0003-2032-7775
George GiannakoulasCardiology Department, AHEPA University Hospital, Aristotle University of Thessaloniki, 54621 Thessaloniki, Greece.ORCID 0000-0001-7491-6319
Anastasia Anthi1st Department of Critical Care, National & Kapodistrian University of Athens Medical School, Pulmonary Hypertension Clinic Evaggelismos General Hospital, 10676 Athens, Greece.
Alexandra ArvanitakiCardiology Department, AHEPA University Hospital, Aristotle University of Thessaloniki, 54621 Thessaloniki, Greece.
George AthanassopoulosCardiology Department, Onassis Cardiac Surgery Center, 17674 Athens, Greece.
Christos FeloukidisCardiology Department, AHEPA University Hospital, Aristotle University of Thessaloniki, 54621 Thessaloniki, Greece.ORCID 0000-0002-3313-5468
Ioannis IakovouCardiology Department, Onassis Cardiac Surgery Center, 17674 Athens, Greece.
Theodora KostelidouCardiology Department, Onassis Cardiac Surgery Center, 17674 Athens, Greece.
Ioanna MitrouskaDepartment of Intensive Care Medicine, University Hospital of Heraklion, 71110 Heraklion, Greece.
Sophia-Anastasia MouratoglouCardiology Department, AHEPA University Hospital, Aristotle University of Thessaloniki, 54621 Thessaloniki, Greece.ORCID 0000-0001-7804-8352
Stylianos E Orfanos1st Department of Critical Care, National & Kapodistrian University of Athens Medical School, Pulmonary Hypertension Clinic Evaggelismos General Hospital, 10676 Athens, Greece.
Christos PappasMultidisciplinary Pulmonary Hypertension Center, Attikon University General Hospital, 12461 Athens, Greece.
Georgia PitsiouRespiratory Failure Unit, "G. Papanikolaou" Hospital, 57010 Thessaloniki, Greece.ORCID 0000-0001-7426-0890
Eleftheria-Garyfallia TsetikaCardiology Department, Onassis Cardiac Surgery Center, 17674 Athens, Greece.
Dimitrios TsiaprasCardiology Department, Onassis Cardiac Surgery Center, 17674 Athens, Greece.ORCID 0000-0001-8192-9839
Vassilios VoudrisCardiology Department, Onassis Cardiac Surgery Center, 17674 Athens, Greece.
Athanassios ManginasCardiology Department, Mediterraneo Hospital, 16675 Athens, Greece.
Hellenic Society for the Study of Pulmonary Hypertension HSSPH
Onassis Cardiac Surgery Center · GRAristotle University of Thessaloniki · GRNational and Kapodistrian University of Athens · GRG. Papanikolaou General Hospital · GRUniversity General Hospital Attikon · GRUniversity Hospital of Heraklion · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Balloon pulmonary angioplasty (BPA) is a novel and promising treatment option for patients with chronic thromboembolic pulmonary hypertension (CTEPH) who are ineligible for pulmonary endarterectomy (PEA) and for those with persistent or recurrent pulmonary hypertension after PEA. We present the results of BPA procedures in CTEPH patients included in the Greek Pulmonary Hypertension Registry, evaluating the real-life efficacy and safety. We analyzed data from 180 BPA procedures (2−17/patient, mean 8 ± 4/patient, 1248 dilated vessels, 0−18/session). Significant improvements were observed in mean pulmonary arterial pressure (a reduction by 44%, p < 0.001), pulmonary vascular resistance (reduction by 60%, p < 0.001), and NT-proBNP (decrease by >70%, p: 0.003), while cardiac index improved modestly (9% increase, p = 0.143). We had 37 BPA-related non-fatal complications (20.6% in all interventions), predominantly including hemoptysis. Overall survival was 91%, 75% and 62% at 3, 4 and 5 years, respectively. Therefore, BPA may be a promising therapeutic option in patients with CTEPH in Greece.

Indexed as

balloon pulmonary angioplastychronic thromboembolic pulmonary hypertensionpulmonary hypertensionregistry

Identifiers

PMID35456303
PMCPMC9028480
OpenAlexW4223934776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.